Prognostic role of the extent of peritumoral vascular invasion in operable breast cancer

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The clinical relevance of the degree of peritumoral vascular invasion (PVI) in patients with no or limited involvement of the axillary nodes is unknown. Materials and methods: 2606 consecutive patients with pT1-3, pN0 (1586)-1a (1020) and M0, operated and counseled for medical therapy from 1/2000 to 12/2002, were prospectively classified according to the degree of PVI: absent (2017, 77.4%), focal (368, 14.1%), moderate (51, 2.0%) and extensive (170, 6.5%). Results: Patients with extensive PVI were more likely to be younger, to have larger tumors, high tumor grade, axillary-positive nodes, high Ki-67 expression and HER2/neu over-expression compared with patients having less PVI (P for trend,

Original languageEnglish
Pages (from-to)1632-1640
Number of pages9
JournalAnnals of Oncology
Volume18
Issue number10
DOIs
Publication statusPublished - Oct 2007

Keywords

  • Breast cancer
  • Peritumoral vascular invasion
  • Prognostic factor

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Prognostic role of the extent of peritumoral vascular invasion in operable breast cancer'. Together they form a unique fingerprint.

Cite this