Prognostic role of tumor size in childhood cancer

Francesca Favini, Iyad Sultan, Cristina Meazza, Michela Casanova, Andrea Ferrari

Research output: Contribution to journalArticlepeer-review

Abstract

Identifying prognostic factors that influence outcome is a key point in pediatric oncology, as it enables risk stratification and helps us to fine-tune risk-adapted treatments, thereby hopefully improving the chances of survival for high-risk patients, and minimizing the burden of treatment for those whose outlook is good. Along with other clinical and biological variables, tumor size at onset has been identified as a crucial variable in several pediatric malignancies, and in soft-tissue sarcomas in particular. This review provides a critical reappraisal of the prognostic role of tumor size in pediatric soft-tissue sarcomas.

Original languageEnglish
Pages (from-to)1605-1613
Number of pages9
JournalFuture Oncology
Volume5
Issue number10
DOIs
Publication statusPublished - 2009

Keywords

  • Pediatric cancer
  • Prognostic factors
  • Rhabdomyosarcoma
  • Risk stratification
  • Risk-adapted treatment
  • Soft-tissue sarcoma
  • Survival
  • Tumor size

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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