Prognostic significance of lymphatic spread in head and neck carcinomas: therapeutic implications.

C. Grandi, M. Alloisio, D. Moglia, S. Podrecca, L. Sala, P. Salvatori, R. Molinari

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Abstract

A series of 618 patients with neck dissections were performed in 455 consecutively admitted patients with head and neck carcinomas at the Istituto Nazionale Tumori, Milan, from 1976 to 1978. Clinical and pathologic node factors were considered in an effort to correlate lymph node involvement with prognosis. Actuarial survival decreased with the increase in the size of nodes, although no significant difference was found for all categories and the prognosis was poor when nodes were greater than 5 cm and/or hypomobile (33%, 5-year survival). The presence of histologically proven neck metastases significantly reduces the 5-year survival, and the presence of distant metastases correlates directly with the pathologic staging of neck nodes.

Original languageEnglish
Pages (from-to)67-73
Number of pages7
JournalHead and Neck
Volume8
Issue number2
Publication statusPublished - Nov 1985

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ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Grandi, C., Alloisio, M., Moglia, D., Podrecca, S., Sala, L., Salvatori, P., & Molinari, R. (1985). Prognostic significance of lymphatic spread in head and neck carcinomas: therapeutic implications. Head and Neck, 8(2), 67-73.