Prognostic significance of lymphatic spread in head and neck carcinomas: therapeutic implications.

C. Grandi, M. Alloisio, D. Moglia, S. Podrecca, L. Sala, P. Salvatori, R. Molinari

Research output: Contribution to journalArticle

Abstract

A series of 618 patients with neck dissections were performed in 455 consecutively admitted patients with head and neck carcinomas at the Istituto Nazionale Tumori, Milan, from 1976 to 1978. Clinical and pathologic node factors were considered in an effort to correlate lymph node involvement with prognosis. Actuarial survival decreased with the increase in the size of nodes, although no significant difference was found for all categories and the prognosis was poor when nodes were greater than 5 cm and/or hypomobile (33%, 5-year survival). The presence of histologically proven neck metastases significantly reduces the 5-year survival, and the presence of distant metastases correlates directly with the pathologic staging of neck nodes.

Original languageEnglish
Pages (from-to)67-73
Number of pages7
JournalHead and Neck
Volume8
Issue number2
Publication statusPublished - Nov 1985

Fingerprint

Neck
Head
Carcinoma
Survival
Neoplasm Metastasis
Neck Dissection
Therapeutics
Lymph Nodes

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Grandi, C., Alloisio, M., Moglia, D., Podrecca, S., Sala, L., Salvatori, P., & Molinari, R. (1985). Prognostic significance of lymphatic spread in head and neck carcinomas: therapeutic implications. Head and Neck, 8(2), 67-73.

Prognostic significance of lymphatic spread in head and neck carcinomas : therapeutic implications. / Grandi, C.; Alloisio, M.; Moglia, D.; Podrecca, S.; Sala, L.; Salvatori, P.; Molinari, R.

In: Head and Neck, Vol. 8, No. 2, 11.1985, p. 67-73.

Research output: Contribution to journalArticle

Grandi, C, Alloisio, M, Moglia, D, Podrecca, S, Sala, L, Salvatori, P & Molinari, R 1985, 'Prognostic significance of lymphatic spread in head and neck carcinomas: therapeutic implications.', Head and Neck, vol. 8, no. 2, pp. 67-73.
Grandi C, Alloisio M, Moglia D, Podrecca S, Sala L, Salvatori P et al. Prognostic significance of lymphatic spread in head and neck carcinomas: therapeutic implications. Head and Neck. 1985 Nov;8(2):67-73.
Grandi, C. ; Alloisio, M. ; Moglia, D. ; Podrecca, S. ; Sala, L. ; Salvatori, P. ; Molinari, R. / Prognostic significance of lymphatic spread in head and neck carcinomas : therapeutic implications. In: Head and Neck. 1985 ; Vol. 8, No. 2. pp. 67-73.
@article{45e450234f76459b821b8afca11d0d38,
title = "Prognostic significance of lymphatic spread in head and neck carcinomas: therapeutic implications.",
abstract = "A series of 618 patients with neck dissections were performed in 455 consecutively admitted patients with head and neck carcinomas at the Istituto Nazionale Tumori, Milan, from 1976 to 1978. Clinical and pathologic node factors were considered in an effort to correlate lymph node involvement with prognosis. Actuarial survival decreased with the increase in the size of nodes, although no significant difference was found for all categories and the prognosis was poor when nodes were greater than 5 cm and/or hypomobile (33{\%}, 5-year survival). The presence of histologically proven neck metastases significantly reduces the 5-year survival, and the presence of distant metastases correlates directly with the pathologic staging of neck nodes.",
author = "C. Grandi and M. Alloisio and D. Moglia and S. Podrecca and L. Sala and P. Salvatori and R. Molinari",
year = "1985",
month = "11",
language = "English",
volume = "8",
pages = "67--73",
journal = "Head and Neck Surgery",
issn = "1043-3074",
publisher = "Wiley-Liss Inc.",
number = "2",

}

TY - JOUR

T1 - Prognostic significance of lymphatic spread in head and neck carcinomas

T2 - therapeutic implications.

AU - Grandi, C.

AU - Alloisio, M.

AU - Moglia, D.

AU - Podrecca, S.

AU - Sala, L.

AU - Salvatori, P.

AU - Molinari, R.

PY - 1985/11

Y1 - 1985/11

N2 - A series of 618 patients with neck dissections were performed in 455 consecutively admitted patients with head and neck carcinomas at the Istituto Nazionale Tumori, Milan, from 1976 to 1978. Clinical and pathologic node factors were considered in an effort to correlate lymph node involvement with prognosis. Actuarial survival decreased with the increase in the size of nodes, although no significant difference was found for all categories and the prognosis was poor when nodes were greater than 5 cm and/or hypomobile (33%, 5-year survival). The presence of histologically proven neck metastases significantly reduces the 5-year survival, and the presence of distant metastases correlates directly with the pathologic staging of neck nodes.

AB - A series of 618 patients with neck dissections were performed in 455 consecutively admitted patients with head and neck carcinomas at the Istituto Nazionale Tumori, Milan, from 1976 to 1978. Clinical and pathologic node factors were considered in an effort to correlate lymph node involvement with prognosis. Actuarial survival decreased with the increase in the size of nodes, although no significant difference was found for all categories and the prognosis was poor when nodes were greater than 5 cm and/or hypomobile (33%, 5-year survival). The presence of histologically proven neck metastases significantly reduces the 5-year survival, and the presence of distant metastases correlates directly with the pathologic staging of neck nodes.

UR - http://www.scopus.com/inward/record.url?scp=0022156342&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022156342&partnerID=8YFLogxK

M3 - Article

C2 - 4077553

AN - SCOPUS:0022156342

VL - 8

SP - 67

EP - 73

JO - Head and Neck Surgery

JF - Head and Neck Surgery

SN - 1043-3074

IS - 2

ER -