Prognostic significance of serum creatinine and its change patterns in patients with acute coronary syndromes

Giancarlo Marenzi; Angelo Cabiati; Nicola Cosentino; Emilio Assanelli; Valentina Milazzo; Mara Rubino; Gianfranco Lauri; Marco Morpurgo; Marco Moltrasio; Ivana Marana; Monica De Metrio; Alice Bonomi; Fabrizio Veglia; Antonio Bartorelli

doi:10.1016/j.ahj.2014.11.019

Prognostic significance of serum creatinine and its change patterns in patients with acute coronary syndromes

Giancarlo Marenzi, Angelo Cabiati, Nicola Cosentino, Emilio Assanelli, Valentina Milazzo, Mara Rubino, Gianfranco Lauri, Marco Morpurgo, Marco Moltrasio, Ivana Marana, Monica De Metrio, Alice Bonomi, Fabrizio Veglia, Antonio Bartorelli

Centro Cardiologico Monzino

Research output: Contribution to journal › Article › peer-review

Abstract

Background In acute coronary syndromes (ACS), serum creatinine (sCr) levels have short- and long-term prognostic value. However, it is possible that repeated evaluations of sCr during hospitalization, rather than measuring sCr value at admission only, might improve risk assessment. We investigated the relationship between sCr baseline value, its changes, and in-hospital mortality in patients hospitalized with ACS. Methods In 2,756 ACS patients, sCr was measured at hospital admission and then daily, until discharge from coronary care unit. Patients were grouped according to the maximum sCr change observed:

Original language	English
Pages (from-to)	363-370
Number of pages	8
Journal	American Heart Journal
Volume	169
Issue number	3
DOIs	https://doi.org/10.1016/j.ahj.2014.11.019
Publication status	Published - Mar 1 2015

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Medicine(all)

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10.1016/j.ahj.2014.11.019

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Marenzi, G., Cabiati, A., Cosentino, N., Assanelli, E., Milazzo, V., Rubino, M., Lauri, G., Morpurgo, M., Moltrasio, M., Marana, I., De Metrio, M., Bonomi, A., Veglia, F., & Bartorelli, A. (2015). Prognostic significance of serum creatinine and its change patterns in patients with acute coronary syndromes. American Heart Journal, 169(3), 363-370. https://doi.org/10.1016/j.ahj.2014.11.019

Marenzi, G, Cabiati, A, Cosentino, N , Assanelli, E , Milazzo, V , Rubino, M , Lauri, G, Morpurgo, M, Moltrasio, M , Marana, I , De Metrio, M , Bonomi, A , Veglia, F & Bartorelli, A 2015, 'Prognostic significance of serum creatinine and its change patterns in patients with acute coronary syndromes', American Heart Journal, vol. 169, no. 3, pp. 363-370. https://doi.org/10.1016/j.ahj.2014.11.019

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abstract = "Background In acute coronary syndromes (ACS), serum creatinine (sCr) levels have short- and long-term prognostic value. However, it is possible that repeated evaluations of sCr during hospitalization, rather than measuring sCr value at admission only, might improve risk assessment. We investigated the relationship between sCr baseline value, its changes, and in-hospital mortality in patients hospitalized with ACS. Methods In 2,756 ACS patients, sCr was measured at hospital admission and then daily, until discharge from coronary care unit. Patients were grouped according to the maximum sCr change observed: ",

author = "Giancarlo Marenzi and Angelo Cabiati and Nicola Cosentino and Emilio Assanelli and Valentina Milazzo and Mara Rubino and Gianfranco Lauri and Marco Morpurgo and Marco Moltrasio and Ivana Marana and {De Metrio}, Monica and Alice Bonomi and Fabrizio Veglia and Antonio Bartorelli",

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T1 - Prognostic significance of serum creatinine and its change patterns in patients with acute coronary syndromes

AU - Marenzi, Giancarlo

AU - Cabiati, Angelo

AU - Cosentino, Nicola

AU - Assanelli, Emilio

AU - Milazzo, Valentina

AU - Rubino, Mara

AU - Lauri, Gianfranco

AU - Morpurgo, Marco

AU - Moltrasio, Marco

AU - Marana, Ivana

AU - De Metrio, Monica

AU - Bonomi, Alice

AU - Veglia, Fabrizio

AU - Bartorelli, Antonio

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Background In acute coronary syndromes (ACS), serum creatinine (sCr) levels have short- and long-term prognostic value. However, it is possible that repeated evaluations of sCr during hospitalization, rather than measuring sCr value at admission only, might improve risk assessment. We investigated the relationship between sCr baseline value, its changes, and in-hospital mortality in patients hospitalized with ACS. Methods In 2,756 ACS patients, sCr was measured at hospital admission and then daily, until discharge from coronary care unit. Patients were grouped according to the maximum sCr change observed:

AB - Background In acute coronary syndromes (ACS), serum creatinine (sCr) levels have short- and long-term prognostic value. However, it is possible that repeated evaluations of sCr during hospitalization, rather than measuring sCr value at admission only, might improve risk assessment. We investigated the relationship between sCr baseline value, its changes, and in-hospital mortality in patients hospitalized with ACS. Methods In 2,756 ACS patients, sCr was measured at hospital admission and then daily, until discharge from coronary care unit. Patients were grouped according to the maximum sCr change observed:

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Prognostic significance of serum creatinine and its change patterns in patients with acute coronary syndromes

Abstract

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