Prognostic stratification of patients with ST-segment-elevation myocardial infarction (PROSPECT): A cardiac magnetic resonance study

G. Pontone, A.I. Guaricci, D. Andreini, G. Ferro, M. Guglielmo, A. Baggiano, L. Fusini, G. Muscogiuri, V. Lorenzoni, S. Mushtaq, E. Conte, A. Annoni, A. Formenti, M.E. Mancini, P. Carità, M. Verdecchia, S. Pica, F. Fazzari, N. Cosentino, G. MarenziM.G. Rabbat, P. Agostoni, A.L. Bartorelli, M. Pepi, P.G. Masci

Research output: Contribution to journalArticlepeer-review


Background-Cardiac magnetic resonance (CMR) is a robust tool to evaluate left ventricular ejection fraction (LVEF), myocardial salvage index, microvascular obstruction, and myocardial hemorrhage in patients with ST-segment-elevation myocardial infarction. We evaluated the additional prognostic benefit of a CMR score over standard prognostic stratification with global registry of acute coronary events (GRACE) score and transthoracic echocardiography LVEF measurement. Methods and Results-Two hundred nine consecutive patients with ST-segment-elevation myocardial infarction (age, 61.4±11.4 years; 162 men) underwent transthoracic echocardiography and CMR after succesful primary percutaneous coronary intervention. Major adverse cardiac events (MACE) were assessed at a mean follow-up of 2.5±1.2 years. MACE occurred in 24 (12%) patients who at baseline showed higher GRACE risk score (P
Original languageEnglish
JournalCirculation: Cardiovascular Imaging
Issue number11
Publication statusPublished - 2017


  • Humans
  • Magnetic resonance
  • Prognosis
  • ST-segment-elevation myocardial infarction
  • gadobenate dimeglumine
  • gadobenic acid
  • adult
  • Article
  • blood vessel occlusion
  • cardiovascular magnetic resonance
  • controlled study
  • coronary angiography
  • female
  • heart left ventricle ejection fraction
  • heart left ventricle mass
  • human
  • major adverse cardiac event
  • major clinical study
  • male
  • middle aged
  • myocardial hemorrhage
  • myocardial salvage index
  • percutaneous coronary intervention
  • priority journal
  • ST segment elevation myocardial infarction
  • transthoracic echocardiography
  • aged
  • bleeding
  • chi square distribution
  • cine magnetic resonance imaging
  • comparative study
  • coronary artery blood flow
  • diagnostic imaging
  • echocardiography
  • heart left ventricle function
  • heart stroke volume
  • microcirculation
  • multivariate analysis
  • pathophysiology
  • predictive value
  • proportional hazards model
  • risk factor
  • time factor
  • treatment outcome
  • Aged
  • Chi-Square Distribution
  • Coronary Angiography
  • Coronary Circulation
  • Echocardiography
  • Female
  • Hemorrhage
  • Magnetic Resonance Imaging, Cine
  • Male
  • Microcirculation
  • Middle Aged
  • Multivariate Analysis
  • Percutaneous Coronary Intervention
  • Predictive Value of Tests
  • Proportional Hazards Models
  • Risk Factors
  • ST Elevation Myocardial Infarction
  • Stroke Volume
  • Time Factors
  • Treatment Outcome
  • Ventricular Function, Left


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