VALORE PROGNOSTICO DELL'EEG DINAMICO DURANTE LA SOSPENSIONE DI FARMACI ANTIEPILETTICI

Translated title of the contribution: Prognostic value of ambulatory cassette recording during withdrawal of anticonvulsivant drugs

M. T. Faedda, C. Iani, L. Fusco, A. T. Giallonardo, L. Pacifici, D. Mattia, P. Quarato, M. Manfredi

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of this study is to verify if 24 hours ambulatory EEG (A/EEG) is more reliable than conventional 30-60 min EEG (C/EEG) is assessing the risk of relapse during withdrawal of AED. Thirty-two pts with a diagnosis of epilepsy have been selected. The pts were on therapy and seizure free for at least three years. Twenty-eight pts concluded the study (14 with generalized and 14 with partial epilepsy). Withdrawal of AED took place over a period of nine months, A/EEG C/EEG being recorded every three months. The recordings were evaluated in a blind fashion. Relapses have been observed in 7pts with generalized epilepsy and in 9 with partial epilepsy. A/EEG but not C/EEG showed a good correlation with the outcome. Worsening or appearence of abnormalities took place in 10 out of 16 relapsing pts (4 with generalized and 6 with partial epilepsy), and only in 4 out of 12 pts still free of seizures after 2-4 years of follow-up.

Translated title of the contributionPrognostic value of ambulatory cassette recording during withdrawal of anticonvulsivant drugs
Original languageItalian
Pages (from-to)273-274
Number of pages2
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number74
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Clinical Neurology

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