The purpose of this study is to verify if 24 hours ambulatory EEG (A/EEG) is more reliable than conventional 30-60 min EEG (C/EEG) is assessing the risk of relapse during withdrawal of AED. Thirty-two pts with a diagnosis of epilepsy have been selected. The pts were on therapy and seizure free for at least three years. Twenty-eight pts concluded the study (14 with generalized and 14 with partial epilepsy). Withdrawal of AED took place over a period of nine months, A/EEG C/EEG being recorded every three months. The recordings were evaluated in a blind fashion. Relapses have been observed in 7pts with generalized epilepsy and in 9 with partial epilepsy. A/EEG but not C/EEG showed a good correlation with the outcome. Worsening or appearence of abnormalities took place in 10 out of 16 relapsing pts (4 with generalized and 6 with partial epilepsy), and only in 4 out of 12 pts still free of seizures after 2-4 years of follow-up.
|Translated title of the contribution||Prognostic value of ambulatory cassette recording during withdrawal of anticonvulsivant drugs|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1991|
ASJC Scopus subject areas
- Clinical Neurology