Valore prognostico dell'angiografia coronarica mediante tomografia computerizzata in pazienti con dolore toracico di sospetta origine coronarica

Translated title of the contribution: Prognostic value of computed tomography coronary angiography in patients with chest pain of suspected cardiac origin

E. Maffei, S. Seitun, C. Martini, A. Aldrovandi, G. Cervellin, C. Tedeschi, A. Guaricci, G. Messalli, O. Catalano, F. Cademartiri

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: The authors sought to determine the prognostic value of computed tomography coronary angiography (CTCA) in patients with acute chest pain (ACP). Materials and methods: A total of 145 consecutive patients (75 men; 64±12 years) with ACP were referred from the Emergency Department for CTCA, which was performed with a standard protocol using a 64-slice scanner. Patients were stratified according to the Morise clinical score (low, intermediate, high) and to the CTCA findings [absence of coronary artery disease (CAD), nonobstructive CAD, obstructive CAD]. Patients were followed up for the occurrence of major events: cardiac death, nonfatal myocardial infarction, unstable angina and revascularisation. Results: One hundred and twenty-seven (87.6%) patients were without a history of CAD, and 18 (12.4%) patients had a history of CAD. Obstructive CAD (>50% luminal narrowing) was detected in 35 (24%) patients; nonobstructive CAD (≤50% luminal narrowing) in 62 (43%) and absence of CAD in 48 (33%) patients. During a mean follow-up of 20±3 months, 20 events occurred (four hard events). Sixteen events (three hard events) occurred in patients without a history of CAD, and four events (one hard event) occurred in patients with a history of CAD. In patients with absence of CAD as detected by CTCA, the rate of events was 0%. At multivariate analysis, hypercholesterolaemia and obstructive CAD were significant predictors of events (p

Translated title of the contributionPrognostic value of computed tomography coronary angiography in patients with chest pain of suspected cardiac origin
Original languageItalian
Pages (from-to)690-705
Number of pages16
JournalRadiologia Medica
Volume116
Issue number5
DOIs
Publication statusPublished - Aug 2011

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

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