Prognostic value of dipyridamole stress cardiac magnetic resonance in patients with known or suspected coronary artery disease: a mid-term follow-up study

Gianluca Pontone, Daniele Andreini, Erika Bertella, Monica Loguercio, Marco Guglielmo, Andrea Baggiano, Giovanni Donato Aquaro, Saima Mushtaq, Sara Salerni, Paola Gripari, Carmen Rossi, Chiara Segurini, Edoardo Conte, Virginia Beltrama, Marta Giovannardi, Fabrizio Veglia, Andrea Igoren Guaricci, Antonio L. Bartorelli, Piergiuseppe Agostoni, Mauro PepiPier Giorgio Masci

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Objectives: Dipyridamole stress cardiac magnetic resonance (CMR) evaluates the key phases (perfusion and wall motion) of the ischemic cascade. We sought to determine the prognostic value of dipyridamole stress-CMR in consecutive patients symptomatic for chest pain. Methods: Seven hundred and ninety-three consecutive patients symptomatic for chest pain underwent dipyridamole stress-CMR and were followed up for 810 ± 665 days. Patients were classified in group 1 (no- reversible ischemia), group 2 (stress perfusion defect alone), and group 3 [stress perfusion defect plus abnormal wall motion (AWM)]. End points were "all cardiac events" (myocardial infarction, cardiac death and revascularization) and "hard cardiac events" (all cardiac events excluding revascularization). Results: One hundred and ninety-five (24 %) all cardiac events and 53 (7 %) hard cardiac events were observed. All and hard cardiac event rates in groups 1, 2, and 3 were 11 %, 49 %, 69 % and 4 %, 8 %, 21 %, respectively, with a higher rate in group 2 vs. group 1 (p

Original languageEnglish
JournalEuropean Radiology
DOIs
Publication statusAccepted/In press - Oct 29 2015

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Dipyridamole
Coronary Artery Disease
Magnetic Resonance Spectroscopy
Perfusion
Chest Pain
Ischemia
Myocardial Infarction

Keywords

  • Coronary artery disease
  • Magnetic resonance
  • Myocardial ischemia
  • Myocardial perfusion imaging
  • Prognosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Prognostic value of dipyridamole stress cardiac magnetic resonance in patients with known or suspected coronary artery disease : a mid-term follow-up study. / Pontone, Gianluca; Andreini, Daniele; Bertella, Erika; Loguercio, Monica; Guglielmo, Marco; Baggiano, Andrea; Aquaro, Giovanni Donato; Mushtaq, Saima; Salerni, Sara; Gripari, Paola; Rossi, Carmen; Segurini, Chiara; Conte, Edoardo; Beltrama, Virginia; Giovannardi, Marta; Veglia, Fabrizio; Guaricci, Andrea Igoren; Bartorelli, Antonio L.; Agostoni, Piergiuseppe; Pepi, Mauro; Masci, Pier Giorgio.

In: European Radiology, 29.10.2015.

Research output: Contribution to journalArticle

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abstract = "Objectives: Dipyridamole stress cardiac magnetic resonance (CMR) evaluates the key phases (perfusion and wall motion) of the ischemic cascade. We sought to determine the prognostic value of dipyridamole stress-CMR in consecutive patients symptomatic for chest pain. Methods: Seven hundred and ninety-three consecutive patients symptomatic for chest pain underwent dipyridamole stress-CMR and were followed up for 810 ± 665 days. Patients were classified in group 1 (no- reversible ischemia), group 2 (stress perfusion defect alone), and group 3 [stress perfusion defect plus abnormal wall motion (AWM)]. End points were {"}all cardiac events{"} (myocardial infarction, cardiac death and revascularization) and {"}hard cardiac events{"} (all cardiac events excluding revascularization). Results: One hundred and ninety-five (24 {\%}) all cardiac events and 53 (7 {\%}) hard cardiac events were observed. All and hard cardiac event rates in groups 1, 2, and 3 were 11 {\%}, 49 {\%}, 69 {\%} and 4 {\%}, 8 {\%}, 21 {\%}, respectively, with a higher rate in group 2 vs. group 1 (p",
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T2 - a mid-term follow-up study

AU - Pontone, Gianluca

AU - Andreini, Daniele

AU - Bertella, Erika

AU - Loguercio, Monica

AU - Guglielmo, Marco

AU - Baggiano, Andrea

AU - Aquaro, Giovanni Donato

AU - Mushtaq, Saima

AU - Salerni, Sara

AU - Gripari, Paola

AU - Rossi, Carmen

AU - Segurini, Chiara

AU - Conte, Edoardo

AU - Beltrama, Virginia

AU - Giovannardi, Marta

AU - Veglia, Fabrizio

AU - Guaricci, Andrea Igoren

AU - Bartorelli, Antonio L.

AU - Agostoni, Piergiuseppe

AU - Pepi, Mauro

AU - Masci, Pier Giorgio

PY - 2015/10/29

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N2 - Objectives: Dipyridamole stress cardiac magnetic resonance (CMR) evaluates the key phases (perfusion and wall motion) of the ischemic cascade. We sought to determine the prognostic value of dipyridamole stress-CMR in consecutive patients symptomatic for chest pain. Methods: Seven hundred and ninety-three consecutive patients symptomatic for chest pain underwent dipyridamole stress-CMR and were followed up for 810 ± 665 days. Patients were classified in group 1 (no- reversible ischemia), group 2 (stress perfusion defect alone), and group 3 [stress perfusion defect plus abnormal wall motion (AWM)]. End points were "all cardiac events" (myocardial infarction, cardiac death and revascularization) and "hard cardiac events" (all cardiac events excluding revascularization). Results: One hundred and ninety-five (24 %) all cardiac events and 53 (7 %) hard cardiac events were observed. All and hard cardiac event rates in groups 1, 2, and 3 were 11 %, 49 %, 69 % and 4 %, 8 %, 21 %, respectively, with a higher rate in group 2 vs. group 1 (p

AB - Objectives: Dipyridamole stress cardiac magnetic resonance (CMR) evaluates the key phases (perfusion and wall motion) of the ischemic cascade. We sought to determine the prognostic value of dipyridamole stress-CMR in consecutive patients symptomatic for chest pain. Methods: Seven hundred and ninety-three consecutive patients symptomatic for chest pain underwent dipyridamole stress-CMR and were followed up for 810 ± 665 days. Patients were classified in group 1 (no- reversible ischemia), group 2 (stress perfusion defect alone), and group 3 [stress perfusion defect plus abnormal wall motion (AWM)]. End points were "all cardiac events" (myocardial infarction, cardiac death and revascularization) and "hard cardiac events" (all cardiac events excluding revascularization). Results: One hundred and ninety-five (24 %) all cardiac events and 53 (7 %) hard cardiac events were observed. All and hard cardiac event rates in groups 1, 2, and 3 were 11 %, 49 %, 69 % and 4 %, 8 %, 21 %, respectively, with a higher rate in group 2 vs. group 1 (p

KW - Coronary artery disease

KW - Magnetic resonance

KW - Myocardial ischemia

KW - Myocardial perfusion imaging

KW - Prognosis

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