Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 847-853 |
| Number of pages | 7 |
| Journal | Diabetes Care |
| Volume | 41 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 1 2018 |
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Prognostic value of the acute-to-chronic glycemic ratio at admission in acute myocardial infarction: A prospective study. / Marenzi, Giancarlo Silvio; Cosentino, Nicola; Milazzo, Valentina; De Metrio, Monica; Rubino, Mara; Campodonico, Jeness; Moltrasio, Marco; Marana, Ivana; grazi, mauro; Bonomi, Alice; Veglia, Fabrizio; manfrini, roberto; Bartorelli, Antonio.
In: Diabetes Care, Vol. 41, No. 4, 01.04.2018, p. 847-853.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Prognostic value of the acute-to-chronic glycemic ratio at admission in acute myocardial infarction: A prospective study
AU - Marenzi, Giancarlo Silvio
AU - Cosentino, Nicola
AU - Milazzo, Valentina
AU - De Metrio, Monica
AU - Rubino, Mara
AU - Campodonico, Jeness
AU - Moltrasio, Marco
AU - Marana, Ivana
AU - grazi, mauro
AU - Bonomi, Alice
AU - Veglia, Fabrizio
AU - manfrini, roberto
AU - Bartorelli, Antonio
PY - 2018/4/1
Y1 - 2018/4/1
N2 - © 2018 by the American Diabetes Association. OBJECTIVE Acute hyperglycemia is a powerful predictor of poor prognosis in acute myocardial infarction (AMI), particularly in patients without diabetes. This emphasizes the importance of an acute glycemic rise rather than glycemia level at admission alone.We investigated in AMI whether the combined evaluation of acute and chronic glycemic levels, as compared with admission glycemia alone, may have a better prognostic value. RESEARCH DESIGN AND METHODS We prospectively measured admission glycemia and estimated average chronic glucose levels (mg/dL) by the following formula: [(28.7×glycosylated hemoglobin %)-46.7], and calculated the acute-to-chronic (A/C) glycemic ratio in 1,553 consecutive AMI patients (mean±SD age 67±13 years). The primary end pointwas the combination of in-hospital mortality, acute pulmonary edema, and cardiogenic shock. RESULTS The primary end point rate increased in parallel with A/C glycemic ratio tertiles (5%, 8%, and 20%, respectively; P for trend
AB - © 2018 by the American Diabetes Association. OBJECTIVE Acute hyperglycemia is a powerful predictor of poor prognosis in acute myocardial infarction (AMI), particularly in patients without diabetes. This emphasizes the importance of an acute glycemic rise rather than glycemia level at admission alone.We investigated in AMI whether the combined evaluation of acute and chronic glycemic levels, as compared with admission glycemia alone, may have a better prognostic value. RESEARCH DESIGN AND METHODS We prospectively measured admission glycemia and estimated average chronic glucose levels (mg/dL) by the following formula: [(28.7×glycosylated hemoglobin %)-46.7], and calculated the acute-to-chronic (A/C) glycemic ratio in 1,553 consecutive AMI patients (mean±SD age 67±13 years). The primary end pointwas the combination of in-hospital mortality, acute pulmonary edema, and cardiogenic shock. RESULTS The primary end point rate increased in parallel with A/C glycemic ratio tertiles (5%, 8%, and 20%, respectively; P for trend
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U2 - 10.2337/dc17-1732
DO - 10.2337/dc17-1732
M3 - Article
C2 - 29382659
AN - SCOPUS:85044541827
VL - 41
SP - 847
EP - 853
JO - Diabetes Care
JF - Diabetes Care
SN - 1935-5548
IS - 4
ER -