Prognostic Value of the Diverticular Disease Severity Score Based on CT Colonography: Follow-up in Patients Recovering from Acute Diverticulitis

Nicola Flor, Giovanni Maconi, Francesco Sardanelli, Maria Antonietta Lombardi, Bernardo Colombo, Giovanni Di Leo, Monica Falleni, Gianpaolo Cornalba, Perry J. Pickhardt

Research output: Contribution to journalArticlepeer-review

Abstract

Rationale and Objectives: To assess the prognostic value of a diverticular disease severity score (DDSS) based on computed tomography colonography (CTC) after acute diverticulitis (AD). Materials and Methods: Of 252 patients who had an AD episode, we finally selected 46 patients who underwent both conventional CT at the acute event and CTC after 9 ± 7 weeks. Of these 46 patients, 17 underwent elective surgery after CTC. Disease severity was assessed with a 0-4 modified Hinchey CT-based score and a 1-4 CTC-based DDSS. A phone survey was performed 27 months later (range 4-52) for the 29 patients not surgically treated. Results: Significant correlation was found between CTC-based DDSS and clinical follow-up (P = 0.022) or elective surgery (P = 0.007), but not between clinical follow-up and CT-based score, extraluminal gas, C-reactive protein serum level, age, gender, or first versus recurrent AD episode. CTC demonstrated relevant additional findings in five of 46 (11%) patients: two AD complications (enterocolic and enterotubal fistulae), two colon cancers, and one extracolonic (lung) cancer. Conclusion: sThe CTC-based DDSS showed a prognostic value and correlated with the risk of undergoing surgery, and clinically relevant additional findings were found in more than 10% of patients. CTC could be the preferred test in patients recovering after AD.

Original languageEnglish
Pages (from-to)1503-1509
Number of pages7
JournalAcademic Radiology
Volume22
Issue number12
DOIs
Publication statusPublished - Dec 1 2015

Keywords

  • Abdominal CT
  • Acute diverticulitis
  • Colon
  • CT colonography
  • Diverticular disease

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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