Programmed cellular death (apoptosis) and endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate

M. Lazzeri, D. Turini, L. Sineo

Research output: Contribution to journalArticle

Abstract

In recent years exciting doors to future discoveries and treatment of various cancers have been opened in the field of molecular medicine. In particular for prostate cancer, the second most common cause of death from tumours in USA, the inhibitor genes of cellular death and peptides which are mediators of the cellular cycle by paracrine and/or autocrine effect, have become a major focus in biomedical research. In this article we examine the role of the bcl-2 gene and Endothelin-1 in the pathophysiology of metastatic adenocarcinoma of the prostate.

Original languageEnglish
Pages (from-to)175-178
Number of pages4
JournalActa Urologica Italica
Volume10
Issue number2
Publication statusPublished - 1996

Keywords

  • apoptosis
  • bcl-2
  • endothelin-1
  • prostate carcinoma

ASJC Scopus subject areas

  • Urology

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