Progression of renal damage in glycogen storage disease type i is associated to hyperlipidemia: A multicenter prospective Italian study

Daniela Melis, Mariarosaria Cozzolino, Giorgia Minopoli, Francesca Balivo, Rossella Parini, Miriam Rigoldi, Sabrina Paci, Carlo Dionisi-Vici, Alberto Burlina, Generoso Andria, Giancarlo Parenti

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Angiotensin converting enzyme (ACE)-inhibitors decrease glomerular hyperfiltration but not microalbuminuria and proteinuria in glycogen storage disease type I. In the current study, we demonstrated that severe hyperlipidemia is associated with ACE-inhibitor ineffectiveness. We underline the importance of adequate metabolic control in glycogen storage disease type I. A combination therapy with ACE-inhibitors and lipid lowering drugs might be considered.

Original languageEnglish
Pages (from-to)1079-1082
Number of pages4
JournalJournal of Pediatrics
Volume166
Issue number4
DOIs
Publication statusPublished - 2015

Fingerprint

Glycogen Storage Disease
Glycogen Storage Disease Type I
Hyperlipidemias
Angiotensin-Converting Enzyme Inhibitors
Prospective Studies
Kidney
Proteinuria
Lipids
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Progression of renal damage in glycogen storage disease type i is associated to hyperlipidemia : A multicenter prospective Italian study. / Melis, Daniela; Cozzolino, Mariarosaria; Minopoli, Giorgia; Balivo, Francesca; Parini, Rossella; Rigoldi, Miriam; Paci, Sabrina; Dionisi-Vici, Carlo; Burlina, Alberto; Andria, Generoso; Parenti, Giancarlo.

In: Journal of Pediatrics, Vol. 166, No. 4, 2015, p. 1079-1082.

Research output: Contribution to journalArticle

Melis, D, Cozzolino, M, Minopoli, G, Balivo, F, Parini, R, Rigoldi, M, Paci, S, Dionisi-Vici, C, Burlina, A, Andria, G & Parenti, G 2015, 'Progression of renal damage in glycogen storage disease type i is associated to hyperlipidemia: A multicenter prospective Italian study', Journal of Pediatrics, vol. 166, no. 4, pp. 1079-1082. https://doi.org/10.1016/j.jpeds.2014.12.015
Melis, Daniela ; Cozzolino, Mariarosaria ; Minopoli, Giorgia ; Balivo, Francesca ; Parini, Rossella ; Rigoldi, Miriam ; Paci, Sabrina ; Dionisi-Vici, Carlo ; Burlina, Alberto ; Andria, Generoso ; Parenti, Giancarlo. / Progression of renal damage in glycogen storage disease type i is associated to hyperlipidemia : A multicenter prospective Italian study. In: Journal of Pediatrics. 2015 ; Vol. 166, No. 4. pp. 1079-1082.
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