Progressive brain failure after diffuse hypoxic ischemic brain injury: A serial MR and proton MR spectroscopic study

A. Falini, A. J. Barkovich, G. Calabrese, D. Origgi, F. Triulzi, G. Scotti

Research output: Contribution to journalArticle

Abstract

The findings at sequential MR imaging and proton MR spectroscopy of a patient with profound hypoxic-ischemic brain injury are reported. The pattern of structural and biochemical changes observed closely reflected the known evolution of postasphyxic brain degeneration. Particularly noteworthy were the sharp decrease of cortical N-acetylaspartate in the acute phase, suggesting the severity of the neuronal insult, and the subsequent progressive increase of choline, paralleling the delayed degeneration of white matter.

Original languageEnglish
Pages (from-to)648-652
Number of pages5
JournalAmerican Journal of Neuroradiology
Volume19
Issue number4
Publication statusPublished - Apr 1998

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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