Progressive parkinsonism, oculomotor abnormalities and autonomic dysfunction: Clinicopathological case

Giovanni Fabbrini; Marcello Merello; Andrew H. Evans; Andrew J. Lees; Janice Holton; David R. Williams

doi:10.1002/mds.23302

Progressive parkinsonism, oculomotor abnormalities and autonomic dysfunction: Clinicopathological case

Giovanni Fabbrini, Marcello Merello, Andrew H. Evans, Andrew J. Lees, Janice Holton, David R. Williams

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Abstract

A 59-year-old woman presented with asymmetric parkinsonism that was not-responsive to Levodopa therapy. She developed early falls, postural instability, and moderately severe autonomic dysfunction. Eye movement abnormalities were reported 2 years after her first symptoms, and she eventually developed anterocollis. Experts discuss the syndromal diagnosis and predict the underlying pathology. The pathological diagnosis is given and clinical learning points are considered.

Original language	English
Pages (from-to)	424-429
Number of pages	6
Journal	Movement Disorders
Volume	26
Issue number	3
DOIs	https://doi.org/10.1002/mds.23302
Publication status	Published - Feb 15 2011

Keywords

Clinicopathological case
MSA
PSP

ASJC Scopus subject areas

Clinical Neurology
Neurology

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10.1002/mds.23302

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abstract = "A 59-year-old woman presented with asymmetric parkinsonism that was not-responsive to Levodopa therapy. She developed early falls, postural instability, and moderately severe autonomic dysfunction. Eye movement abnormalities were reported 2 years after her first symptoms, and she eventually developed anterocollis. Experts discuss the syndromal diagnosis and predict the underlying pathology. The pathological diagnosis is given and clinical learning points are considered.",

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AU - Merello, Marcello

AU - Evans, Andrew H.

AU - Lees, Andrew J.

AU - Holton, Janice

AU - Williams, David R.

PY - 2011/2/15

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AB - A 59-year-old woman presented with asymmetric parkinsonism that was not-responsive to Levodopa therapy. She developed early falls, postural instability, and moderately severe autonomic dysfunction. Eye movement abnormalities were reported 2 years after her first symptoms, and she eventually developed anterocollis. Experts discuss the syndromal diagnosis and predict the underlying pathology. The pathological diagnosis is given and clinical learning points are considered.

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KW - PSP

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Progressive parkinsonism, oculomotor abnormalities and autonomic dysfunction: Clinicopathological case

Abstract

Keywords

ASJC Scopus subject areas

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