Progressive visual function impairment as the predominant symptom of the transition phase to secondary progressive multiple sclerosis: A case report

A Giordano, B Colombo, EG Spinelli, S Gelibter, Simone Guerrieri, L Leocani, G Comi, V Martinelli

Research output: Contribution to journalArticle

Abstract

Background: No reliable indicators of the transition to the progressive course in multiple sclerosis (MS) have been identified so far. The main clinical feature of the progressive phase of MS is usually impairment of walking. Magnetic resonance imaging and optical coherence tomography have emerged recently as promising tools to assess increasing neurodegeneration and axonal loss in disease progression in MS. Methods. Case report. Results. We report a case of progressive visual impairment as the dominant symptom in the transition to secondary progressive MS. Conclusions. Impairment of vision, together with walking and cognition, should be considered to better define the transition from relapsing/remitting to secondary-progressive MS. © 2018 Elsevier B.V.
Original languageEnglish
Pages (from-to)69-71
Number of pages3
JournalMultiple Sclerosis and Related Disorders
Volume24
Issue number2
DOIs
Publication statusPublished - 2018

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Chronic Progressive Multiple Sclerosis
Vision Disorders
Phase Transition
Multiple Sclerosis
Walking
Optical Coherence Tomography
Cognition
Disease Progression
Magnetic Resonance Imaging

Cite this

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title = "Progressive visual function impairment as the predominant symptom of the transition phase to secondary progressive multiple sclerosis: A case report",
abstract = "Background: No reliable indicators of the transition to the progressive course in multiple sclerosis (MS) have been identified so far. The main clinical feature of the progressive phase of MS is usually impairment of walking. Magnetic resonance imaging and optical coherence tomography have emerged recently as promising tools to assess increasing neurodegeneration and axonal loss in disease progression in MS. Methods. Case report. Results. We report a case of progressive visual impairment as the dominant symptom in the transition to secondary progressive MS. Conclusions. Impairment of vision, together with walking and cognition, should be considered to better define the transition from relapsing/remitting to secondary-progressive MS. {\circledC} 2018 Elsevier B.V.",
author = "A Giordano and B Colombo and EG Spinelli and S Gelibter and Simone Guerrieri and L Leocani and G Comi and V Martinelli",
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TY - JOUR

T1 - Progressive visual function impairment as the predominant symptom of the transition phase to secondary progressive multiple sclerosis: A case report

AU - Giordano, A

AU - Colombo, B

AU - Spinelli, EG

AU - Gelibter, S

AU - Guerrieri, Simone

AU - Leocani, L

AU - Comi, G

AU - Martinelli, V

PY - 2018

Y1 - 2018

N2 - Background: No reliable indicators of the transition to the progressive course in multiple sclerosis (MS) have been identified so far. The main clinical feature of the progressive phase of MS is usually impairment of walking. Magnetic resonance imaging and optical coherence tomography have emerged recently as promising tools to assess increasing neurodegeneration and axonal loss in disease progression in MS. Methods. Case report. Results. We report a case of progressive visual impairment as the dominant symptom in the transition to secondary progressive MS. Conclusions. Impairment of vision, together with walking and cognition, should be considered to better define the transition from relapsing/remitting to secondary-progressive MS. © 2018 Elsevier B.V.

AB - Background: No reliable indicators of the transition to the progressive course in multiple sclerosis (MS) have been identified so far. The main clinical feature of the progressive phase of MS is usually impairment of walking. Magnetic resonance imaging and optical coherence tomography have emerged recently as promising tools to assess increasing neurodegeneration and axonal loss in disease progression in MS. Methods. Case report. Results. We report a case of progressive visual impairment as the dominant symptom in the transition to secondary progressive MS. Conclusions. Impairment of vision, together with walking and cognition, should be considered to better define the transition from relapsing/remitting to secondary-progressive MS. © 2018 Elsevier B.V.

U2 - 10.1016/j.msard.2018.06.011

DO - 10.1016/j.msard.2018.06.011

M3 - Article

VL - 24

SP - 69

EP - 71

JO - Multiple Sclerosis and Related Disorders

JF - Multiple Sclerosis and Related Disorders

SN - 2211-0348

IS - 2

ER -