Prolactin in CSF selectively increases dopamine turnover in the median eminence

L. Annunziato, K. E. Moore

Research output: Contribution to journalArticle

Abstract

The α-methyltyrosine-induced decline of dopamine was increased in the median eminence of rats at 16 but not at 2 hours after the start of intraventricular injections of 0.2-2 μg of rat prolactin. Intraventricular injections of prolactin did not alter the α-methyltyrosine-induced decline of dopamine in the striatum or olfactory tubercle. These results suggest that prolactin in the cerebrospinal fluid can selectively increase the activity of tuberoinfundibular dopaminergic neurons.

Original languageEnglish
Pages (from-to)2037-2041
Number of pages5
JournalLife Sciences
Volume22
Issue number22
DOIs
Publication statusPublished - Jun 12 1978

ASJC Scopus subject areas

  • Pharmacology

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