TY - JOUR
T1 - Proliferative Radiation Retinopathy after Plaque Radiotherapy for Uveal Melanoma
AU - Bianciotto, Carlos
AU - Shields, Carol L.
AU - Pirondini, Cesare
AU - Mashayekhi, Arman
AU - Furuta, Minoru
AU - Shields, Jerry A.
PY - 2010/5
Y1 - 2010/5
N2 - Purpose: To determine risk factors, occurrence rate, management, and outcome of proliferative radiation retinopathy (PRR) after plaque radiotherapy for uveal melanoma. Design: Case-control study. Participants: Three thousand eight hundred forty-one patients who underwent plaque radiotherapy for uveal melanoma were entered into the study. Methods: Retrospective review of medical records. Main Outcome Measures: Proliferative radiation retinopathy after plaque radiotherapy for uveal melanoma. Results: Of 3841 eyes treated with plaque radiotherapy for uveal melanoma, PRR developed in 5.8% at 5 years and in 7% at 10 and 15 years using Kaplan-Meier analysis. The mean time to onset of PRR was 32 months (median, 30 months; range, 4-88 months). On univariate analysis, baseline factors predictive of PRR (P
AB - Purpose: To determine risk factors, occurrence rate, management, and outcome of proliferative radiation retinopathy (PRR) after plaque radiotherapy for uveal melanoma. Design: Case-control study. Participants: Three thousand eight hundred forty-one patients who underwent plaque radiotherapy for uveal melanoma were entered into the study. Methods: Retrospective review of medical records. Main Outcome Measures: Proliferative radiation retinopathy after plaque radiotherapy for uveal melanoma. Results: Of 3841 eyes treated with plaque radiotherapy for uveal melanoma, PRR developed in 5.8% at 5 years and in 7% at 10 and 15 years using Kaplan-Meier analysis. The mean time to onset of PRR was 32 months (median, 30 months; range, 4-88 months). On univariate analysis, baseline factors predictive of PRR (P
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U2 - 10.1016/j.ophtha.2009.10.015
DO - 10.1016/j.ophtha.2009.10.015
M3 - Article
C2 - 20079924
AN - SCOPUS:77951622412
VL - 117
SP - 1005
EP - 1012
JO - Ophthalmology
JF - Ophthalmology
SN - 0161-6420
IS - 5
ER -