Prolonged focal negative motor seizures: A video-EEG study

Flavio Villani, Domenico D'Amico, Alessandro Pincherle, Vincenzo Tullo, Luisa Chiapparini, Gennaro Bussone

Research output: Contribution to journalArticlepeer-review


Purpose: Focal negative motor (akinetic) seizures are rare ictal events that are diagnostically challenging because they are difficult to differentiate from postictal Todd paresis, transient ischemic attacks, migraine events, and psychogenic episodes. Methods: We describe a 45-year-old man in whom, after surgical drainage of a right frontoparietal subdural hematoma, prolonged episodes developed with flaccid paralysis of the left arm. Results: A video-EEG recording demonstrated a close relation between the focal motor impairment and a clear-cut epileptic ictal discharge involving the right perirolandic cortical areas. Conclusions: On the basis of the electroclinical data, we hypothesize the involvement of the primary motor area in the genesis of the epileptic discharge triggering focal negative seizures.

Original languageEnglish
Pages (from-to)1949-1952
Number of pages4
Issue number11
Publication statusPublished - Nov 2006


  • Focal epilepsy
  • Ictal paralysis
  • Negative seizures
  • Prolonged seizures
  • Todd paresis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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