Prolonged muscular flaccidity in stroke patients is associated with crossed cerebellar diaschisis

Patrizia Pantano, Rita Formisano, Monica Ricci, Piero Barbanti, Marco Fiorelli, Umberto Sabatini, Vittorio Di Piero, Gian Luigi Lenzi

Research output: Contribution to journalArticlepeer-review


In order to evaluate whether hypotonia could be the clinical expression of crossed cerebellar diaschisis (CCD), we studied the occurrence and severity of CCD in two groups of hemiparetic stroke patients presenting either with prolonged muscular flaccidity (PMF, n = 14) or with muscular spasticity (MSp, n = 13) over the affected hemisoma. CCD was more frequent and severe in hypotonic than in spastic patients. Neither the time elapsed from the stroke nor the volume of the lesion was significantly different between patients with PMF and those with MSp. The two groups of patients showed different motor deficit scores, but motor deficit severity and CCD did not correlate. We concluded that the persistence of CCD after stroke may be associated with PMF, emphasizing the link between functional cerebellar impairment and muscular hypotonia.

Original languageEnglish
Pages (from-to)80-85
Number of pages6
JournalCerebrovascular Diseases
Issue number2
Publication statusPublished - 1993


  • Crossed cerebellar diaschisis
  • Ischemic stroke
  • Prolonged muscular flaccidity
  • Single-photon emission tomography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Neurology


Dive into the research topics of 'Prolonged muscular flaccidity in stroke patients is associated with crossed cerebellar diaschisis'. Together they form a unique fingerprint.

Cite this