Abstract
Atypical adenomatous hyperplasia (AAH) is a putative precursor of bronchioloalveolar carcinoma (BAC) and adenocarcinoma of the lung, developing from terminal respiratory unit cells. AAH and BAC lesions typically present as ground-glass opacities at spiral chest computed tomography. Epidermal growth factor receptor polysomy/mutations, conferring higher sensitivity to Gefitinib, are frequent in BAC but less common in AAH. We describe an interesting case of disseminated AAH showing a sustained remission under Gefitinib therapy.
Original language | English |
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Pages (from-to) | 266-267 |
Number of pages | 2 |
Journal | Journal of Thoracic Oncology |
Volume | 4 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb 2009 |
Keywords
- AAH
- BAC
- CT screening
- FISH
- Gefitinib
ASJC Scopus subject areas
- Oncology
- Pulmonary and Respiratory Medicine
- Medicine(all)