Prolonged stabilization of multiple and single brain metastases from breast cancer with tamoxifen. Report of three cases

M. Salvati, L. Cervoni, G. Innocenzi, L. Bardella

Research output: Contribution to journalArticle


Cancer frequently metastasizes to the brain, and such lesions, whether multiple or solitary, have a poor prognosis, despite all efforts to treat them. There have been recent sporadic reports of brain metastases from breast cancer responding for some years to antiestrogens (particularly tamoxifen) or bromocryptine. We report three cases of brain metastasis from cancer - two multiple and one a solitary lesion. The long survival of the patients - two for 5 years and one for 6 years, with more than an acceptable quality of life - should prompt therapeutic trials to test tamoxifen and designed to assess its effects on a sizable number of patients.

Original languageEnglish
Pages (from-to)359-362
Number of pages4
Issue number5
Publication statusPublished - 1993



  • brain metastases
  • breast cancer
  • tamoxifen

ASJC Scopus subject areas

  • Cancer Research

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