Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 2241-2248 |
| Number of pages | 8 |
| Journal | Haematologica |
| Volume | 104 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2019 |
Keywords
- cyclophosphamide plus doxorubicin plus prednisolone plus rituximab plus vincristine
- immunoglobulin
- lactate dehydrogenase
- rituximab
- acute leukemia
- adult
- anaphylaxis
- Article
- autograft
- autologous hematopoietic stem cell transplantation
- cancer growth
- cancer immunotherapy
- cancer staging
- cancer survival
- controlled study
- disease exacerbation
- disease free survival
- female
- follicular lymphoma
- Follicular Lymphoma International Prognostic Index
- follow up
- human
- male
- middle aged
- minimal residual disease
- multicenter study
- myelodysplastic syndrome
- overall survival
- polymerase chain reaction
- prospective study
- randomized controlled trial
- remission
- sudden death
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Prolonged survival in the absence of disease-recurrence in advanced-stage follicular lymphoma following chemo-immunotherapy: 13-year update of the prospective, multicenter randomized GITMO-IIL trial. / Bruna, R.; Benedetti, F.; Boccomini, C.; Patti, C.; Barbui, A.M.; Pulsoni, A.; Musso, M.; Liberati, A.M.; Gini, G.; Castellino, C.; Rossini, F.; Ciceri, F.; Rota-Scalabrini, D.; Stelitano, C.; Di Raimondo, F.; Tucci, A.; Devizzi, L.; Zoli, V.; Zallio, F.; Narni, F.; Dondi, A.; Parvis, G.; Semenzato, G.; Lanza, F.; Perrone, T.; Angrilli, F.; Billio, A.; Gueli, A.; Mantoan, B.; Rambaldi, A.; Massimo Gianni, A.; Corradini, P.; Passera, R.; Ladetto, M.; Tarella, C.
In: Haematologica, Vol. 104, No. 11, 2019, p. 2241-2248.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Prolonged survival in the absence of disease-recurrence in advanced-stage follicular lymphoma following chemo-immunotherapy: 13-year update of the prospective, multicenter randomized GITMO-IIL trial
AU - Bruna, R.
AU - Benedetti, F.
AU - Boccomini, C.
AU - Patti, C.
AU - Barbui, A.M.
AU - Pulsoni, A.
AU - Musso, M.
AU - Liberati, A.M.
AU - Gini, G.
AU - Castellino, C.
AU - Rossini, F.
AU - Ciceri, F.
AU - Rota-Scalabrini, D.
AU - Stelitano, C.
AU - Di Raimondo, F.
AU - Tucci, A.
AU - Devizzi, L.
AU - Zoli, V.
AU - Zallio, F.
AU - Narni, F.
AU - Dondi, A.
AU - Parvis, G.
AU - Semenzato, G.
AU - Lanza, F.
AU - Perrone, T.
AU - Angrilli, F.
AU - Billio, A.
AU - Gueli, A.
AU - Mantoan, B.
AU - Rambaldi, A.
AU - Massimo Gianni, A.
AU - Corradini, P.
AU - Passera, R.
AU - Ladetto, M.
AU - Tarella, C.
N1 - Export Date: 26 February 2020 CODEN: HAEMA Correspondence Address: Tarella, C.; Onco-Hematology Division, IEO, European Institute of Oncology IRCCSItaly; email: corrado.tarella@unimi.it Chemicals/CAS: immunoglobulin, 9007-83-4; lactate dehydrogenase, 9001-60-9; rituximab, 174722-31-7 Funding details: PRIN 2010-2011 Funding text 1: This work was supported in part by the Ministero Italiano Università e Ricerca (MIUR), Rome, Italy (grant PRIN 2010-2011, pr. N.: 2010B5B2NL), and by Banca del Piemonte (Torino, Italy). The initial clinical trial (March 2000 - May 2005) was made possible by Compagnia di San Paolo (Torino, Italy), Regione Piemonte (Torino, Italy), and by Roche (Milan, Italy), which provided free rituximab for all patients. We are indebted to GITMO (Gruppo Italiano Trapianto Midollo Osseo) and to IIL, now merged into FIL (Fondazione Italiana Linfomi) for their fundamental participation in the development and completion of the study. 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PY - 2019
Y1 - 2019
N2 - Aprospective trial conducted in the period 2000-2005 showed no survival advantage for high-dose chemotherapy with rituximab and autograft (RHDS) versus conventional chemotherapy with rituximab (CHOP-R) as firstline therapy in 134 high-risk follicular lymphoma patients aged
AB - Aprospective trial conducted in the period 2000-2005 showed no survival advantage for high-dose chemotherapy with rituximab and autograft (RHDS) versus conventional chemotherapy with rituximab (CHOP-R) as firstline therapy in 134 high-risk follicular lymphoma patients aged
KW - cyclophosphamide plus doxorubicin plus prednisolone plus rituximab plus vincristine
KW - immunoglobulin
KW - lactate dehydrogenase
KW - rituximab
KW - acute leukemia
KW - adult
KW - anaphylaxis
KW - Article
KW - autograft
KW - autologous hematopoietic stem cell transplantation
KW - cancer growth
KW - cancer immunotherapy
KW - cancer staging
KW - cancer survival
KW - controlled study
KW - disease exacerbation
KW - disease free survival
KW - female
KW - follicular lymphoma
KW - Follicular Lymphoma International Prognostic Index
KW - follow up
KW - human
KW - male
KW - middle aged
KW - minimal residual disease
KW - multicenter study
KW - myelodysplastic syndrome
KW - overall survival
KW - polymerase chain reaction
KW - prospective study
KW - randomized controlled trial
KW - remission
KW - sudden death
U2 - 10.3324/haematol.2018.209932
DO - 10.3324/haematol.2018.209932
M3 - Article
VL - 104
SP - 2241
EP - 2248
JO - Haematologica
JF - Haematologica
SN - 0390-6078
IS - 11
ER -