Propafenone for supraventricular arrhythmias in septic shock-Comparison to amiodarone and metoprolol

M. Balik; I. Kolnikova; M. Maly; P. Waldauf; G. Tavazzi; J. Kristof

doi:S0883-9441(17)30136-3 [pii]

Propafenone for supraventricular arrhythmias in septic shock-Comparison to amiodarone and metoprolol

M. Balik, I. Kolnikova, M. Maly, P. Waldauf, G. Tavazzi, J. Kristof

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

PURPOSE: The occurence of supraventricular arrhythmias associate with an unfavourable prognosis in septic shock. Propafenone could be a feasible antiarrhythmic. MATERIALS AND METHODS: Patients collected over a period of 24months were divided into the three groups based on antiarrhythmic: Group1(amiodarone), Group2(propafenone), Group3(metoprolol). Type of arrhythmia, cardioversion rates, demographic, haemodynamic, laboratory parameters were recorded in the first 24h. The outcome data were compared between the groups. RESULTS: 234 patients (99.1% ventilated) were included, the prevailing arrhythmia was acute onset atrial fibrillation (AF,69.7%). Except for the dosage of noradrenaline (0.35(0.14-0.78) in Group1(n=142)vs 0.25(0.10-0.50),p

Original language	English
Pages (from-to)	16-23
Number of pages	8
Journal	Journal of Critical Care
Volume	41
DOIs	https://doi.org/S0883-9441(17)30136-3 [pii]
Publication status	Published - Oct 1 2017

Keywords

Amiodarone
Betablockers
Metoprolol
Propafenone
Septic shock
Supraventricular arrhythmia

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title = "Propafenone for supraventricular arrhythmias in septic shock-Comparison to amiodarone and metoprolol",

abstract = "PURPOSE: The occurence of supraventricular arrhythmias associate with an unfavourable prognosis in septic shock. Propafenone could be a feasible antiarrhythmic. MATERIALS AND METHODS: Patients collected over a period of 24months were divided into the three groups based on antiarrhythmic: Group1(amiodarone), Group2(propafenone), Group3(metoprolol). Type of arrhythmia, cardioversion rates, demographic, haemodynamic, laboratory parameters were recorded in the first 24h. The outcome data were compared between the groups. RESULTS: 234 patients (99.1% ventilated) were included, the prevailing arrhythmia was acute onset atrial fibrillation (AF,69.7%). Except for the dosage of noradrenaline (0.35(0.14-0.78) in Group1(n=142)vs 0.25(0.10-0.50),p",

keywords = "Amiodarone, Betablockers, Metoprolol, Propafenone, Septic shock, Supraventricular arrhythmia",

author = "M. Balik and I. Kolnikova and M. Maly and P. Waldauf and G. Tavazzi and J. Kristof",

note = "LR: 20171009; CI: Copyright (c) 2017; JID: 8610642; OTO: NOTNLM; 2017/01/30 00:00 [received]; 2017/03/11 00:00 [revised]; 2017/04/20 00:00 [accepted]; 2017/05/04 06:00 [pubmed]; 2017/05/04 06:00 [medline]; 2017/05/03 06:00 [entrez]; ppublish",

year = "2017",

month = oct,

day = "1",

doi = "S0883-9441(17)30136-3 [pii]",

language = "English",

volume = "41",

pages = "16--23",

journal = "Journal of Critical Care",

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TY - JOUR

T1 - Propafenone for supraventricular arrhythmias in septic shock-Comparison to amiodarone and metoprolol

AU - Balik, M.

AU - Kolnikova, I.

AU - Maly, M.

AU - Waldauf, P.

AU - Tavazzi, G.

AU - Kristof, J.

N1 - LR: 20171009; CI: Copyright (c) 2017; JID: 8610642; OTO: NOTNLM; 2017/01/30 00:00 [received]; 2017/03/11 00:00 [revised]; 2017/04/20 00:00 [accepted]; 2017/05/04 06:00 [pubmed]; 2017/05/04 06:00 [medline]; 2017/05/03 06:00 [entrez]; ppublish

PY - 2017/10/1

Y1 - 2017/10/1

N2 - PURPOSE: The occurence of supraventricular arrhythmias associate with an unfavourable prognosis in septic shock. Propafenone could be a feasible antiarrhythmic. MATERIALS AND METHODS: Patients collected over a period of 24months were divided into the three groups based on antiarrhythmic: Group1(amiodarone), Group2(propafenone), Group3(metoprolol). Type of arrhythmia, cardioversion rates, demographic, haemodynamic, laboratory parameters were recorded in the first 24h. The outcome data were compared between the groups. RESULTS: 234 patients (99.1% ventilated) were included, the prevailing arrhythmia was acute onset atrial fibrillation (AF,69.7%). Except for the dosage of noradrenaline (0.35(0.14-0.78) in Group1(n=142)vs 0.25(0.10-0.50),p

AB - PURPOSE: The occurence of supraventricular arrhythmias associate with an unfavourable prognosis in septic shock. Propafenone could be a feasible antiarrhythmic. MATERIALS AND METHODS: Patients collected over a period of 24months were divided into the three groups based on antiarrhythmic: Group1(amiodarone), Group2(propafenone), Group3(metoprolol). Type of arrhythmia, cardioversion rates, demographic, haemodynamic, laboratory parameters were recorded in the first 24h. The outcome data were compared between the groups. RESULTS: 234 patients (99.1% ventilated) were included, the prevailing arrhythmia was acute onset atrial fibrillation (AF,69.7%). Except for the dosage of noradrenaline (0.35(0.14-0.78) in Group1(n=142)vs 0.25(0.10-0.50),p

KW - Amiodarone

KW - Betablockers

KW - Metoprolol

KW - Propafenone

KW - Septic shock

KW - Supraventricular arrhythmia

U2 - S0883-9441(17)30136-3 [pii]

DO - S0883-9441(17)30136-3 [pii]

M3 - Article

VL - 41

SP - 16

EP - 23

JO - Journal of Critical Care

JF - Journal of Critical Care

SN - 0883-9441

ER -