Propafenone for supraventricular arrhythmias in septic shock-Comparison to amiodarone and metoprolol

M. Balik, I. Kolnikova, M. Maly, P. Waldauf, G. Tavazzi, J. Kristof

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: The occurence of supraventricular arrhythmias associate with an unfavourable prognosis in septic shock. Propafenone could be a feasible antiarrhythmic. MATERIALS AND METHODS: Patients collected over a period of 24months were divided into the three groups based on antiarrhythmic: Group1(amiodarone), Group2(propafenone), Group3(metoprolol). Type of arrhythmia, cardioversion rates, demographic, haemodynamic, laboratory parameters were recorded in the first 24h. The outcome data were compared between the groups. RESULTS: 234 patients (99.1% ventilated) were included, the prevailing arrhythmia was acute onset atrial fibrillation (AF,69.7%). Except for the dosage of noradrenaline (0.35(0.14-0.78) in Group1(n=142)vs 0.25(0.10-0.50),p
Original languageEnglish
Pages (from-to)16-23
Number of pages8
JournalJournal of Critical Care
Volume41
DOIs
Publication statusPublished - Oct 1 2017

Keywords

  • Amiodarone
  • Betablockers
  • Metoprolol
  • Propafenone
  • Septic shock
  • Supraventricular arrhythmia

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