Abstract
Background: Liver resection is a potentially curative approach for hepatocellular carcinoma (HCC). Laparoscopic liver resections may reduce complication rates, especially in patients with cirrhosis. The aim of this study was to compare the results of laparoscopic liver resection with those of open liver resection for HCC. Methods: Patients with cirrhosis who underwent minor liver resections for HCC from 2006 to 2013 were identified retrospectively from a prospective database according to the technique adopted (laparoscopic or open). Short- and long-term outcomes were compared between the two groups before and after 1:1 propensity score matching. Results: A total of 269 patients were considered: 226 who underwent open liver resection and 43 who had a laparoscopic procedure. The two groups differed at baseline in terms of median age, sex, performance status, tumour location and type of resection. After propensity score matching, two comparable groups of 43 patients each were obtained. Intraoperative bleeding, margin clearance and operative mortality were similar in the two groups, whereas complication rates were lower (49 versus 19 per cent in open versus laparoscopic groups respectively; P=0·004) and median hospital stay was shorter (8 versus 5 days; P
| Original language | English |
|---|---|
| Journal | British Journal of Surgery |
| DOIs | |
| Publication status | Accepted/In press - 2016 |
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ASJC Scopus subject areas
- Surgery
Cite this
Propensity score analysis of outcomes following laparoscopic or open liver resection for hepatocellular carcinoma. / Sposito, C.; Battiston, C.; Facciorusso, A.; Mazzola, M.; Muscarà, C.; Scotti, M.; Romito, R.; Mariani, L.; Mazzaferro, V.
In: British Journal of Surgery, 2016.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Propensity score analysis of outcomes following laparoscopic or open liver resection for hepatocellular carcinoma
AU - Sposito, C.
AU - Battiston, C.
AU - Facciorusso, A.
AU - Mazzola, M.
AU - Muscarà, C.
AU - Scotti, M.
AU - Romito, R.
AU - Mariani, L.
AU - Mazzaferro, V.
PY - 2016
Y1 - 2016
N2 - Background: Liver resection is a potentially curative approach for hepatocellular carcinoma (HCC). Laparoscopic liver resections may reduce complication rates, especially in patients with cirrhosis. The aim of this study was to compare the results of laparoscopic liver resection with those of open liver resection for HCC. Methods: Patients with cirrhosis who underwent minor liver resections for HCC from 2006 to 2013 were identified retrospectively from a prospective database according to the technique adopted (laparoscopic or open). Short- and long-term outcomes were compared between the two groups before and after 1:1 propensity score matching. Results: A total of 269 patients were considered: 226 who underwent open liver resection and 43 who had a laparoscopic procedure. The two groups differed at baseline in terms of median age, sex, performance status, tumour location and type of resection. After propensity score matching, two comparable groups of 43 patients each were obtained. Intraoperative bleeding, margin clearance and operative mortality were similar in the two groups, whereas complication rates were lower (49 versus 19 per cent in open versus laparoscopic groups respectively; P=0·004) and median hospital stay was shorter (8 versus 5 days; P
AB - Background: Liver resection is a potentially curative approach for hepatocellular carcinoma (HCC). Laparoscopic liver resections may reduce complication rates, especially in patients with cirrhosis. The aim of this study was to compare the results of laparoscopic liver resection with those of open liver resection for HCC. Methods: Patients with cirrhosis who underwent minor liver resections for HCC from 2006 to 2013 were identified retrospectively from a prospective database according to the technique adopted (laparoscopic or open). Short- and long-term outcomes were compared between the two groups before and after 1:1 propensity score matching. Results: A total of 269 patients were considered: 226 who underwent open liver resection and 43 who had a laparoscopic procedure. The two groups differed at baseline in terms of median age, sex, performance status, tumour location and type of resection. After propensity score matching, two comparable groups of 43 patients each were obtained. Intraoperative bleeding, margin clearance and operative mortality were similar in the two groups, whereas complication rates were lower (49 versus 19 per cent in open versus laparoscopic groups respectively; P=0·004) and median hospital stay was shorter (8 versus 5 days; P
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U2 - 10.1002/bjs.10137
DO - 10.1002/bjs.10137
M3 - Article
AN - SCOPUS:84962593999
JO - British Journal of Surgery
JF - British Journal of Surgery
SN - 0007-1323
ER -