Properties of the spike afterhyperpolarization in pyramidal tract neurons

Fausto Baldissera, Paola Campadelli, Enrica Fava, Lino Piccinelli

Research output: Contribution to journalArticle

Abstract

Features of the spike afterhyperpolarization (AHP) recorded intracellularly have been analyzed in fast pyramidal tract neurons of cats. Cell input conductance increases during the AHP, possibly because of a change in potassium conductance, as suggested by an AHP equilibrium potential 10-15 mV negative to the resting membrane potential. When more spikes are evoked in succession, AHPs following the first one are strongly reduced in amplitude. The effect is virtually maximal (30-50% of the control) after a single spike and fades out by 200-400 ms after the last spike. At short interspike intervals the initial time course of the depression is hidden by summation occurring between consecutive AHPs.

Original languageEnglish
Pages (from-to)143-146
Number of pages4
JournalBrain Research
Volume259
Issue number1
DOIs
Publication statusPublished - Jan 17 1983

Keywords

  • afterhyperpolarization
  • intracellular recording
  • potassium conductance
  • pyramidal tract neurons

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Properties of the spike afterhyperpolarization in pyramidal tract neurons'. Together they form a unique fingerprint.

  • Cite this