TY - JOUR
T1 - Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation a randomized clinical trial
AU - Indrio, Flavia
AU - Di Mauro, Antonio
AU - Riezzo, Giuseppe
AU - Civardi, Elisa
AU - Intini, Cristina
AU - Corvaglia, Luigi
AU - Ballardini, Elisa
AU - Bisceglia, Massimo
AU - Cinquetti, Mauro
AU - Brazzoduro, Emanuela
AU - Del Vecchio, Antonio
AU - Tafuri, Silvio
AU - Francavilla, Ruggiero
PY - 2014/3
Y1 - 2014/3
N2 - IMPORTANCE: Infantile colic, gastroesophageal reflux, and constipation are the most common functional gastrointestinal disorders that lead to referral to a pediatrician during the first 6 months of life and are often responsible for hospitalization, feeding changes, use of drugs, parental anxiety, and loss of parental working days with relevant social consequences. OBJECTIVE: To investigate whether oral supplementation with Lactobacillus reuteri DSM 17938 during the first 3 months of life can reduce the onset of colic, gastroesophageal reflux, and constipation in term newborns and thereby reduce the socioeconomic impact of these conditions. DESIGN: A prospective, multicenter, double-masked, placebo-controlled randomized clinical trial was performed on term newborns (age
AB - IMPORTANCE: Infantile colic, gastroesophageal reflux, and constipation are the most common functional gastrointestinal disorders that lead to referral to a pediatrician during the first 6 months of life and are often responsible for hospitalization, feeding changes, use of drugs, parental anxiety, and loss of parental working days with relevant social consequences. OBJECTIVE: To investigate whether oral supplementation with Lactobacillus reuteri DSM 17938 during the first 3 months of life can reduce the onset of colic, gastroesophageal reflux, and constipation in term newborns and thereby reduce the socioeconomic impact of these conditions. DESIGN: A prospective, multicenter, double-masked, placebo-controlled randomized clinical trial was performed on term newborns (age
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U2 - 10.1001/jamapediatrics.2013.4367
DO - 10.1001/jamapediatrics.2013.4367
M3 - Article
C2 - 24424513
AN - SCOPUS:84896758037
VL - 168
SP - 228
EP - 233
JO - JAMA Pediatrics
JF - JAMA Pediatrics
SN - 2168-6203
IS - 3
ER -