Prophylaxis of urinary infection in patients with urinary retention

Because it has long been recognized that a high urinary bladder residue content affects the frequency and duration of urinary infections in cases of urinary retention, study to compare the prophylaxis of the association of an antibacterial agent with an acidifying agent and that of the acidifying agent alone was carried out. Assessment was made of possible relationships between pharmacological effectiveness and mechanical function of the bladder muscle, evaluated using biohumoral and urodynamic tests. There was no significant evidence of variations of urodynamic and biohumoral parameters during the basal and final evaluation, although a clear lower incidence of urinary infections was found in the group treated with the association of antibacterial and acidifying agents together.