Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin: an updated analysis of the EORTC 62091 trial

Antoine Italiano, Nathan Touati, Saskia Litière, Françoise Collin, Philippe Pourquier, Alessandro Gronchi

Research output: Contribution to journalArticle

Abstract

We describe the predictive value of BRCA1 gene status on trabectedin efficacy and found no correlation despite the mechanisms of action of this drug that rely on DNA repair systems.

Original languageEnglish
Pages (from-to)1575-1577
Number of pages3
JournalCancer Medicine
Volume7
Issue number5
DOIs
Publication statusPublished - May 2018

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trabectedin
BRCA1 Gene
DNA Repair
Sarcoma
Pharmaceutical Preparations

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Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin : an updated analysis of the EORTC 62091 trial. / Italiano, Antoine; Touati, Nathan; Litière, Saskia; Collin, Françoise; Pourquier, Philippe; Gronchi, Alessandro.

In: Cancer Medicine, Vol. 7, No. 5, 05.2018, p. 1575-1577.

Research output: Contribution to journalArticle

Italiano, Antoine ; Touati, Nathan ; Litière, Saskia ; Collin, Françoise ; Pourquier, Philippe ; Gronchi, Alessandro. / Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin : an updated analysis of the EORTC 62091 trial. In: Cancer Medicine. 2018 ; Vol. 7, No. 5. pp. 1575-1577.
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