Prospective observational Italian study on palliative sedation in two hospice settings: Differences in casemixes and clinical care

Marco Maltoni, Guido Miccinesi, Piero Morino, Emanuela Scarpi, Francesco Bulli, Francesca Martini, Filippo Canzani, Monia Dall'Agata, Eugenio Paci, Dino Amadori

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose Palliative sedation (PS) has been defined as the use of sedative medications to relieve intolerable suffering from refractory symptoms by a reduction in patient consciousness. It is sometimes necessary in end-of-life care when patients present refractory symptoms. We investigated PS for refractory symptoms in different hospice casemixes in order to (1) assess clinical decision-making, (2) monitor the practice of PS, and (3) examine the impact of PS on survival. Methods This observational longitudinal cohort study was conducted over a period of 9 months on 327 patients consecutively admitted to two 11-bed Italian hospices (A and B) with different casemixes in terms ofmedian patient age (hospice A, 66 years vs. hospice B, 73 years; p=0.005), mean duration of hospice stay (hospice A, 13.5 days vs. hospice B, 18.3 days; p=0.005), and death rate (hospice A, 57.2% vs. hospice B, 89.9%; P

Original languageEnglish
Pages (from-to)2829-2836
Number of pages8
JournalSupportive Care in Cancer
Volume20
Issue number11
DOIs
Publication statusPublished - Nov 2012

Keywords

  • Advanced cancer
  • End-of-life care
  • Hospice casemix
  • Palliative sedation
  • Survival

ASJC Scopus subject areas

  • Oncology

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