TY - JOUR
T1 - Prospective randomized, blind comparison of ropivacaine and levobupivacaine for superficial plexus anesthesia in carotid endoarterectomy
AU - Messina, M.
AU - Magrin, S.
AU - Bignami, E.
AU - Maj, G.
AU - Carozzo, A.
AU - Mennella, R.
AU - Landoni, Giovanni
AU - Zangrillo, A.
PY - 2009/1
Y1 - 2009/1
N2 - Background. The authors performed a study to evaluate if the onset time, duration of sensory block, and quality of postoperative analgesia in superficial cervical plexus anesthesia with 0.5% levobupivacaine (1 mg/ kg) was greater than 0.75% ropivacaine (1.5 mg/kg). Methods. Design: randomized, double-blind study. Setting: University teaching hospital. Participants: 28 consecutive patients undergoing elective carotid thromboendoarterectomy were randomized into two groups. Interventions: patients received either 1 mg/kg of 0.5 % levobupivacaine (N.= 15), or 1.5 mg/kg of 0.75 % ropivacaine (N.= 13). We assessed the onset time (pinprick test), duration of sensory block, and postoperative analgesia with the two drugs. Results. Onset time of sensory block was 20±6 min with ropivacaine and 29±8 min with levobupivacaine (P=0.003). Intraoperatively we used different total doses of lidocaine, with the median (interquartile range) dose of 50 (40-100) mg for ropivacaine and 130 (60-180) mg for levobupivacaine (P=0.05). The first pain medication was requested after 12±0.4 h by ropivacaine patients and after 11±1.6 h by levobupivacaine patients (P=0.5). Conclusion. No beneficial effect was noted in the quality of nerve block or patient's satisfaction for 0.5% levobupivacaine when compared to 0.75% ropivacaine.
AB - Background. The authors performed a study to evaluate if the onset time, duration of sensory block, and quality of postoperative analgesia in superficial cervical plexus anesthesia with 0.5% levobupivacaine (1 mg/ kg) was greater than 0.75% ropivacaine (1.5 mg/kg). Methods. Design: randomized, double-blind study. Setting: University teaching hospital. Participants: 28 consecutive patients undergoing elective carotid thromboendoarterectomy were randomized into two groups. Interventions: patients received either 1 mg/kg of 0.5 % levobupivacaine (N.= 15), or 1.5 mg/kg of 0.75 % ropivacaine (N.= 13). We assessed the onset time (pinprick test), duration of sensory block, and postoperative analgesia with the two drugs. Results. Onset time of sensory block was 20±6 min with ropivacaine and 29±8 min with levobupivacaine (P=0.003). Intraoperatively we used different total doses of lidocaine, with the median (interquartile range) dose of 50 (40-100) mg for ropivacaine and 130 (60-180) mg for levobupivacaine (P=0.05). The first pain medication was requested after 12±0.4 h by ropivacaine patients and after 11±1.6 h by levobupivacaine patients (P=0.5). Conclusion. No beneficial effect was noted in the quality of nerve block or patient's satisfaction for 0.5% levobupivacaine when compared to 0.75% ropivacaine.
KW - Analgesia
KW - Anesthesia conduction
KW - Endarterectomy carotid
KW - Levobupivacaine
KW - Ropivacaine
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M3 - Article
C2 - 19172143
AN - SCOPUS:64549121561
VL - 75
SP - 7
EP - 12
JO - Minerva Anestesiologica
JF - Minerva Anestesiologica
SN - 0375-9393
IS - 1-2
ER -