Prospective study of endocrine side-effects following bone marrow transplantation in childhood

M. Bozzola; F. Locatelli; M. Cisternino; F. Bonetti; D. Gambarana; G. M. Giorgiani Zecca; P. De Stefano; R. Lorini; F. Severi

Prospective study of endocrine side-effects following bone marrow transplantation in childhood

M. Bozzola, F. Locatelli, M. Cisternino, F. Bonetti, D. Gambarana, G. M. Giorgiani Zecca, P. De Stefano, R. Lorini, F. Severi

Research output: Contribution to journal › Article › peer-review

Abstract

An increasing number of children with various hematologic malignancies become long-term survivors following treatment with high dose chemotherapy, total body irradiation (TBI) and bone marrow transplantation (BMT). The doses of chemotherapy and irradiation used in transplant preparative regimens may affect endocrine function. Radiation may directly impair hypothalamic, pituitary, thyroid and gonadal function in a dose-dependent manner. Prospective study is needed to evaluate the long-term endocrine side effects of BMT.

Original language	English
Pages (from-to)	56
Number of pages	1
Journal	Bone Marrow Transplantation
Volume	8
Issue number	SUPPL. 1
Publication status	Published - 1991

ASJC Scopus subject areas

Hematology
Transplantation

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title = "Prospective study of endocrine side-effects following bone marrow transplantation in childhood",

abstract = "An increasing number of children with various hematologic malignancies become long-term survivors following treatment with high dose chemotherapy, total body irradiation (TBI) and bone marrow transplantation (BMT). The doses of chemotherapy and irradiation used in transplant preparative regimens may affect endocrine function. Radiation may directly impair hypothalamic, pituitary, thyroid and gonadal function in a dose-dependent manner. Prospective study is needed to evaluate the long-term endocrine side effects of BMT.",

author = "M. Bozzola and F. Locatelli and M. Cisternino and F. Bonetti and D. Gambarana and {Giorgiani Zecca}, {G. M.} and {De Stefano}, P. and R. Lorini and F. Severi",

year = "1991",

language = "English",

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journal = "Bone Marrow Transplantation",

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T1 - Prospective study of endocrine side-effects following bone marrow transplantation in childhood

AU - Bozzola, M.

AU - Locatelli, F.

AU - Cisternino, M.

AU - Bonetti, F.

AU - Gambarana, D.

AU - Giorgiani Zecca, G. M.

AU - De Stefano, P.

AU - Lorini, R.

AU - Severi, F.

PY - 1991

Y1 - 1991

N2 - An increasing number of children with various hematologic malignancies become long-term survivors following treatment with high dose chemotherapy, total body irradiation (TBI) and bone marrow transplantation (BMT). The doses of chemotherapy and irradiation used in transplant preparative regimens may affect endocrine function. Radiation may directly impair hypothalamic, pituitary, thyroid and gonadal function in a dose-dependent manner. Prospective study is needed to evaluate the long-term endocrine side effects of BMT.

AB - An increasing number of children with various hematologic malignancies become long-term survivors following treatment with high dose chemotherapy, total body irradiation (TBI) and bone marrow transplantation (BMT). The doses of chemotherapy and irradiation used in transplant preparative regimens may affect endocrine function. Radiation may directly impair hypothalamic, pituitary, thyroid and gonadal function in a dose-dependent manner. Prospective study is needed to evaluate the long-term endocrine side effects of BMT.

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