An increasing number of children with various hematologic malignancies become long-term survivors following treatment with high dose chemotherapy, total body irradiation (TBI) and bone marrow transplantation (BMT). The doses of chemotherapy and irradiation used in transplant preparative regimens may affect endocrine function. Radiation may directly impair hypothalamic, pituitary, thyroid and gonadal function in a dose-dependent manner. Prospective study is needed to evaluate the long-term endocrine side effects of BMT.
|Number of pages||1|
|Journal||Bone Marrow Transplantation|
|Issue number||SUPPL. 1|
|Publication status||Published - 1991|
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