Prospective study of endocrine side-effects following bone marrow transplantation in childhood

M. Bozzola, F. Locatelli, M. Cisternino, F. Bonetti, D. Gambarana, G. M. Giorgiani Zecca, P. De Stefano, R. Lorini, F. Severi

Research output: Contribution to journalArticlepeer-review

Abstract

An increasing number of children with various hematologic malignancies become long-term survivors following treatment with high dose chemotherapy, total body irradiation (TBI) and bone marrow transplantation (BMT). The doses of chemotherapy and irradiation used in transplant preparative regimens may affect endocrine function. Radiation may directly impair hypothalamic, pituitary, thyroid and gonadal function in a dose-dependent manner. Prospective study is needed to evaluate the long-term endocrine side effects of BMT.

Original languageEnglish
Pages (from-to)56
Number of pages1
JournalBone Marrow Transplantation
Volume8
Issue numberSUPPL. 1
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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