Prospective study of the detection and treatment of small tumors of the head of the pancreas

C. Bassi, M. Falconi, G. Talamini, R. Salvia, P. Caldiron, L. De Sanctis, A. Bonora, G. Butturini, N. Sartori, C. Procacci, G. Zamboni, P. Pederzoli

Research output: Contribution to journalArticlepeer-review

Abstract

The size of a pancreatic ductal carcinoma is one of the factors that has the greatest impact on the prognosis of the disease. Precise measurement of tumor size in such cases can obviously be achieved only by the pathologist, but, as a result of the increasingly widespread use and refinement of imaging procedures, a fairly accurate preoperative estimate now appears feasible for identifying those lesions which measure ≤2 m in size and which are conventionally defined as "small tumors." At tomography, 15/72 patients (20.8%) with cancer of the head of the pancreas observed in our department over the period 1991 to 1994 were prospectively identified as having tumors measuring ≤2 cm. Histology subsequently confirmed that the growths measured 2 cm or less in size in only 4 of these patients, thus revealing that the imaging technique tended to underestimate the tumor diameters. If we exclude the mean time elapsing from onset of symptoms to diagnosis, which was found to be significantly shorter in small than in non-small tumors (6.3 vs 34.2 days, P

Original languageEnglish
Pages (from-to)347-351
Number of pages5
JournalJournal of Hepato-Biliary-Pancreatic Surgery
Volume2
Issue number4
DOIs
Publication statusPublished - Dec 1995

Keywords

  • diagnosis
  • pancreatic cancer
  • small

ASJC Scopus subject areas

  • Surgery

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