Prospects for specific immunotherapy in myasthenia gravis

L. Steinman, R. Mantegazza

Research output: Contribution to journalArticle

Abstract

Myasthenia gravis is an autoimmune disease resulting from a breakdown in T and B cell tolerance to acetylcholine receptor (AChR). Autoantibodies to AChR mediate the disease. Recent advances in experimental immunotherapy of autoimmune disease provide several possibilities for specific intervention in this well-characterized condition.

Original languageEnglish
Pages (from-to)2726-2731
Number of pages6
JournalFASEB Journal
Volume4
Issue number10
Publication statusPublished - 1990

Keywords

  • antibodies
  • autoimmune response
  • immunotherapy
  • myasthenia gravis
  • T cell tolerance

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Cell Biology

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