Prostate cancer and body size at different ages: An Italian multicentre case-control study

L. Dal Maso, A. Zucchetto, C. La Vecchia, M. Montella, E. Conti, V. Canzonieri, R. Talamini, A. Tavani, E. Negri, A. Garbeglio, S. Franceschi

Research output: Contribution to journalArticlepeer-review

Abstract

We investigated the influence of anthropometric measures at diagnosis and at different ages on prostate cancer risk using an Italian multicentre case-control study conducted between 1991 and 2002 of 1294 histologically confirmed cases and 1451 controls admitted to the same network of hospitals for acute non-neoplastic conditions. Height, weight, body mass index (BMI), waist-to-hip ratio, lean body mass 1 year before diagnosis/interview were not significantly associated with risk. However, a positive association with high BMI at age 30 years was found (odds ratio = 1.2 for BMI ≥ 24.7 vs <22.7) and: for less differentiated prostate cancer, with BMI 1 year before diagnosis/interview. This study supports possible relationships between high body mass in young adulthood, and a tendency to high weight throughout adult life, and the risk of prostate cancer.

Original languageEnglish
Pages (from-to)2176-2180
Number of pages5
JournalBritish Journal of Cancer
Volume90
Issue number11
Publication statusPublished - Jun 1 2004

Keywords

  • Body mass index
  • Case-control study
  • Prostate cancer

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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