TY - JOUR
T1 - Prostatic stromal sarcoma in an adolescent
T2 - The role of chemotherapy
AU - Cavaliere, Elena
AU - Alaggio, Rita
AU - Castagnetti, Marco
AU - Scarzello, Giovanni
AU - Bisogno, Gianni
PY - 2014/10/23
Y1 - 2014/10/23
N2 - Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin- D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.
AB - Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin- D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.
KW - Chemotherapy
KW - Prostatic neoplasm
KW - Specialized prostatic stroma
KW - Stromal sarcoma
UR - http://www.scopus.com/inward/record.url?scp=84919919409&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84919919409&partnerID=8YFLogxK
U2 - 10.4081/rt.2014.5607
DO - 10.4081/rt.2014.5607
M3 - Article
AN - SCOPUS:84919919409
VL - 6
SP - 146
EP - 149
JO - Rare Tumors
JF - Rare Tumors
SN - 2036-3605
IS - 4
M1 - 5607
ER -