Prostatic stromal sarcoma in an adolescent: The role of chemotherapy

Elena Cavaliere, Rita Alaggio, Marco Castagnetti, Giovanni Scarzello, Gianni Bisogno

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Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin- D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.

Original languageEnglish
Article number5607
Pages (from-to)146-149
Number of pages4
JournalRare Tumors
Issue number4
Publication statusPublished - Oct 23 2014


  • Chemotherapy
  • Prostatic neoplasm
  • Specialized prostatic stroma
  • Stromal sarcoma

ASJC Scopus subject areas

  • Oncology
  • Histology


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