Abstract
The protease-antiprotease imbalance is thought to be involved in a variety of destructive lung diseases: pulmonary emphysema, chronic bronchitis, cystic fibrosis and adult respiratory distress syndrome. Bronchoalveolar lavage allowed the investigators to assess the protease-antiprotease shift in such conditions but sometimes gave conflicting results. The role of bronchoalveolar lavage as a research and diagnostic tool in diseases characterised by protease-anti-protease imbalance is reviewed, as well as its potential usefulness in the near future.
Original language | English |
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Pages (from-to) | 24-27 |
Number of pages | 4 |
Journal | Respiration |
Volume | 59 |
DOIs | |
Publication status | Published - 1992 |
Keywords
- Adult respiratory distress syndrome
- Alpha-1 proteinase inhibitor
- Alpha-2 macroglobulin
- Antileukoprotease
- Cathepsin G
- Chronic bronchitis
- Neutrophil elastase
- Pulmonary emphysema
- Sputum sol-phase
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Physiology