Protective effect of inosine administration on ischemic rat liver cell injury

F. Stortoni, R. Rosati, V. Filingeri, F. Svegliati, A. Orlandi, V. Cervelli, C. U. Casciani

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Abstract

Intolerance of the liver to ischemic damage has been documented. Ischemia damage could be an important reason for graft failure. This study was designed to evaluate a potential protective effect of inosine administration on ischemic rat liver cell in comparison with Eurocollins perfusion. If this effect can be demonstrated, inosine could be proven to be of particular value in liver transplantation where the limited period of viability after removal of the organ from the donor is a major factor restricting the diffusion of this surgical procedure.

Original languageEnglish
Pages (from-to)974-976
Number of pages3
JournalTransplantation Proceedings
Volume20
Issue number5
Publication statusPublished - 1988

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ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Stortoni, F., Rosati, R., Filingeri, V., Svegliati, F., Orlandi, A., Cervelli, V., & Casciani, C. U. (1988). Protective effect of inosine administration on ischemic rat liver cell injury. Transplantation Proceedings, 20(5), 974-976.