Protein composition of ascitic fluid in liver cirrhosis

A. Agostoni, B. Marasini, L. Bergamaschini

Research output: Contribution to journalArticle

Abstract

In 59 patients with liver cirrhosis, a marked reduction of prealbumin and an increase of IgA were noted. Treatment with diuretics did not change the pattern of serum proteins. In unconcentrated ascitic fluid, the concentration of individual proteins varied between 13% (α2-macroglobulin) and 26.7% (orosomucoid) of the serum concentration. After a prolonged treatment with diuretics, the concentrations of proteins with higher molecular weights seem to fall (α2-macroglobulin, IgM, IgA) probably owing to a reduction of permeability of hepatic sinusoids or of peritoneal membrane. (Heyrovsky - Prague)

Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalLa Ricerca in Clinica e in Laboratorio
Volume8
Issue numberSUPP.1
Publication statusPublished - 1978

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Macroglobulins
Ascitic Fluid
Diuretics
Liver Cirrhosis
Liver
Immunoglobulin A
Orosomucoid
Prealbumin
Fluids
Chemical analysis
Immunoglobulin M
Blood Proteins
Permeability
Proteins
Molecular Weight
Molecular weight
Membranes
Therapeutics
Serum

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Protein composition of ascitic fluid in liver cirrhosis. / Agostoni, A.; Marasini, B.; Bergamaschini, L.

In: La Ricerca in Clinica e in Laboratorio, Vol. 8, No. SUPP.1, 1978, p. 301-305.

Research output: Contribution to journalArticle

Agostoni, A, Marasini, B & Bergamaschini, L 1978, 'Protein composition of ascitic fluid in liver cirrhosis', La Ricerca in Clinica e in Laboratorio, vol. 8, no. SUPP.1, pp. 301-305.
Agostoni, A. ; Marasini, B. ; Bergamaschini, L. / Protein composition of ascitic fluid in liver cirrhosis. In: La Ricerca in Clinica e in Laboratorio. 1978 ; Vol. 8, No. SUPP.1. pp. 301-305.
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