Protein composition of ascitic fluid in liver cirrhosis

A. Agostoni; B. Marasini; L. Bergamaschini

Protein composition of ascitic fluid in liver cirrhosis

A. Agostoni, B. Marasini, L. Bergamaschini

Istituto Clinico Humanitas

Research output: Contribution to journal › Article › peer-review

Abstract

In 59 patients with liver cirrhosis, a marked reduction of prealbumin and an increase of IgA were noted. Treatment with diuretics did not change the pattern of serum proteins. In unconcentrated ascitic fluid, the concentration of individual proteins varied between 13% (α₂-macroglobulin) and 26.7% (orosomucoid) of the serum concentration. After a prolonged treatment with diuretics, the concentrations of proteins with higher molecular weights seem to fall (α₂-macroglobulin, IgM, IgA) probably owing to a reduction of permeability of hepatic sinusoids or of peritoneal membrane. (Heyrovsky - Prague)

Original language	English
Pages (from-to)	301-305
Number of pages	5
Journal	La Ricerca in Clinica e in Laboratorio
Volume	8
Issue number	SUPP.1
Publication status	Published - 1978

ASJC Scopus subject areas

Clinical Biochemistry

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abstract = "In 59 patients with liver cirrhosis, a marked reduction of prealbumin and an increase of IgA were noted. Treatment with diuretics did not change the pattern of serum proteins. In unconcentrated ascitic fluid, the concentration of individual proteins varied between 13% (α2-macroglobulin) and 26.7% (orosomucoid) of the serum concentration. After a prolonged treatment with diuretics, the concentrations of proteins with higher molecular weights seem to fall (α2-macroglobulin, IgM, IgA) probably owing to a reduction of permeability of hepatic sinusoids or of peritoneal membrane. (Heyrovsky - Prague)",

author = "A. Agostoni and B. Marasini and L. Bergamaschini",

year = "1978",

language = "English",

volume = "8",

pages = "301--305",

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T1 - Protein composition of ascitic fluid in liver cirrhosis

AU - Agostoni, A.

AU - Marasini, B.

AU - Bergamaschini, L.

PY - 1978

Y1 - 1978

N2 - In 59 patients with liver cirrhosis, a marked reduction of prealbumin and an increase of IgA were noted. Treatment with diuretics did not change the pattern of serum proteins. In unconcentrated ascitic fluid, the concentration of individual proteins varied between 13% (α2-macroglobulin) and 26.7% (orosomucoid) of the serum concentration. After a prolonged treatment with diuretics, the concentrations of proteins with higher molecular weights seem to fall (α2-macroglobulin, IgM, IgA) probably owing to a reduction of permeability of hepatic sinusoids or of peritoneal membrane. (Heyrovsky - Prague)

AB - In 59 patients with liver cirrhosis, a marked reduction of prealbumin and an increase of IgA were noted. Treatment with diuretics did not change the pattern of serum proteins. In unconcentrated ascitic fluid, the concentration of individual proteins varied between 13% (α2-macroglobulin) and 26.7% (orosomucoid) of the serum concentration. After a prolonged treatment with diuretics, the concentrations of proteins with higher molecular weights seem to fall (α2-macroglobulin, IgM, IgA) probably owing to a reduction of permeability of hepatic sinusoids or of peritoneal membrane. (Heyrovsky - Prague)

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JO - Ricerca in Clinica e in Laboratorio

JF - Ricerca in Clinica e in Laboratorio

SN - 0940-5437

IS - SUPP.1

ER -

Protein composition of ascitic fluid in liver cirrhosis

Abstract

ASJC Scopus subject areas

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