Abstract
In 59 patients with liver cirrhosis, a marked reduction of prealbumin and an increase of IgA were noted. Treatment with diuretics did not change the pattern of serum proteins. In unconcentrated ascitic fluid, the concentration of individual proteins varied between 13% (α2-macroglobulin) and 26.7% (orosomucoid) of the serum concentration. After a prolonged treatment with diuretics, the concentrations of proteins with higher molecular weights seem to fall (α2-macroglobulin, IgM, IgA) probably owing to a reduction of permeability of hepatic sinusoids or of peritoneal membrane. (Heyrovsky - Prague)
| Original language | English |
|---|---|
| Pages (from-to) | 301-305 |
| Number of pages | 5 |
| Journal | La Ricerca in Clinica e in Laboratorio |
| Volume | 8 |
| Issue number | SUPP.1 |
| Publication status | Published - 1978 |
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ASJC Scopus subject areas
- Clinical Biochemistry
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Protein composition of ascitic fluid in liver cirrhosis. / Agostoni, A.; Marasini, B.; Bergamaschini, L.
In: La Ricerca in Clinica e in Laboratorio, Vol. 8, No. SUPP.1, 1978, p. 301-305.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Protein composition of ascitic fluid in liver cirrhosis
AU - Agostoni, A.
AU - Marasini, B.
AU - Bergamaschini, L.
PY - 1978
Y1 - 1978
N2 - In 59 patients with liver cirrhosis, a marked reduction of prealbumin and an increase of IgA were noted. Treatment with diuretics did not change the pattern of serum proteins. In unconcentrated ascitic fluid, the concentration of individual proteins varied between 13% (α2-macroglobulin) and 26.7% (orosomucoid) of the serum concentration. After a prolonged treatment with diuretics, the concentrations of proteins with higher molecular weights seem to fall (α2-macroglobulin, IgM, IgA) probably owing to a reduction of permeability of hepatic sinusoids or of peritoneal membrane. (Heyrovsky - Prague)
AB - In 59 patients with liver cirrhosis, a marked reduction of prealbumin and an increase of IgA were noted. Treatment with diuretics did not change the pattern of serum proteins. In unconcentrated ascitic fluid, the concentration of individual proteins varied between 13% (α2-macroglobulin) and 26.7% (orosomucoid) of the serum concentration. After a prolonged treatment with diuretics, the concentrations of proteins with higher molecular weights seem to fall (α2-macroglobulin, IgM, IgA) probably owing to a reduction of permeability of hepatic sinusoids or of peritoneal membrane. (Heyrovsky - Prague)
UR - http://www.scopus.com/inward/record.url?scp=0018071648&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018071648&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0018071648
VL - 8
SP - 301
EP - 305
JO - Ricerca in Clinica e in Laboratorio
JF - Ricerca in Clinica e in Laboratorio
SN - 0940-5437
IS - SUPP.1
ER -