Protein composition of ascitic fluid in liver cirrhosis

A. Agostoni, B. Marasini, L. Bergamaschini

Research output: Contribution to journalArticlepeer-review


In 59 patients with liver cirrhosis, a marked reduction of prealbumin and an increase of IgA were noted. Treatment with diuretics did not change the pattern of serum proteins. In unconcentrated ascitic fluid, the concentration of individual proteins varied between 13% (α2-macroglobulin) and 26.7% (orosomucoid) of the serum concentration. After a prolonged treatment with diuretics, the concentrations of proteins with higher molecular weights seem to fall (α2-macroglobulin, IgM, IgA) probably owing to a reduction of permeability of hepatic sinusoids or of peritoneal membrane. (Heyrovsky - Prague)

Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalLa Ricerca in Clinica e in Laboratorio
Issue numberSUPP.1
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Clinical Biochemistry


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