Il contributo della diagnostica proteica nella gestione delle gammopatie monoclonali

Translated title of the contribution: Protein diagnostics in the management of monoclonal gammopathies

Anna Caldini, Maria Stella Graziani, Umberto Basile, Ivana Cataldo, Giovanni Cigliana, Maria Teresa Muratore, Michele Mussap, Alessandro Terreni, Arialdo Vernocchi, Giampaolo Merlini

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

This document examines laboratory tests to be used for the management of monoclonal gammopathies in different clinical scenarios, from screening to monitoring and assessment of the response to therapy. The content is based on international recommendations and guidelines currently available. It includes sections on the analytical aspects of different tests (serum protein electrophoresis, typing and quantification of monoclonal components, Bence Jones protein determination and free light chain measurement) and on their clinical significance as well. Different clinical settings are examined: screening, diagnosis, risk stratification, monitoring and response assessment. For each of those, laboratory tests to be used are indicated. Aim of the document is to help clinical laboratories avoiding unnecessary tests, ensuring in the meantime that all the investigations required for a optimal patient management are carried out.

Original languageItalian
Pages (from-to)47-53
Number of pages7
JournalBiochimica Clinica
Volume38
Issue number1
Publication statusPublished - Feb 2014

Fingerprint

Paraproteinemias
Screening
Bence Jones Protein
Clinical laboratories
Monitoring
Electrophoresis
Blood Proteins
Proteins
Guidelines
Light
Therapeutics

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical
  • Medical Laboratory Technology

Cite this

Caldini, A., Graziani, M. S., Basile, U., Cataldo, I., Cigliana, G., Muratore, M. T., ... Merlini, G. (2014). Il contributo della diagnostica proteica nella gestione delle gammopatie monoclonali. Biochimica Clinica, 38(1), 47-53.

Il contributo della diagnostica proteica nella gestione delle gammopatie monoclonali. / Caldini, Anna; Graziani, Maria Stella; Basile, Umberto; Cataldo, Ivana; Cigliana, Giovanni; Muratore, Maria Teresa; Mussap, Michele; Terreni, Alessandro; Vernocchi, Arialdo; Merlini, Giampaolo.

In: Biochimica Clinica, Vol. 38, No. 1, 02.2014, p. 47-53.

Research output: Contribution to journalArticle

Caldini, A, Graziani, MS, Basile, U, Cataldo, I, Cigliana, G, Muratore, MT, Mussap, M, Terreni, A, Vernocchi, A & Merlini, G 2014, 'Il contributo della diagnostica proteica nella gestione delle gammopatie monoclonali', Biochimica Clinica, vol. 38, no. 1, pp. 47-53.
Caldini A, Graziani MS, Basile U, Cataldo I, Cigliana G, Muratore MT et al. Il contributo della diagnostica proteica nella gestione delle gammopatie monoclonali. Biochimica Clinica. 2014 Feb;38(1):47-53.
Caldini, Anna ; Graziani, Maria Stella ; Basile, Umberto ; Cataldo, Ivana ; Cigliana, Giovanni ; Muratore, Maria Teresa ; Mussap, Michele ; Terreni, Alessandro ; Vernocchi, Arialdo ; Merlini, Giampaolo. / Il contributo della diagnostica proteica nella gestione delle gammopatie monoclonali. In: Biochimica Clinica. 2014 ; Vol. 38, No. 1. pp. 47-53.
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