Protein interaction data curation: The International Molecular Exchange (IMEx) consortium

Sandra Orchard, Samuel Kerrien, Sara Abbani, Bruno Aranda, Jignesh Bhate, Shelby Bidwell, Alan Bridge, Leonardo Briganti, Fiona Brinkman, Gianni Cesareni, Andrew Chatr-Aryamontri, Emilie Chautard, Carol Chen, Marine Dumousseau, Johannes Goll, Robert Hancock, Linda I. Hannick, Igor Jurisica, Jyoti Khadake, David J. LynnUsha Mahadevan, Livia Perfetto, Arathi Raghunath, Sylvie Ricard-Blum, Bernd Roechert, Lukasz Salwinski, Volker Stümpflen, Mike Tyers, Peter Uetz, Ioannis Xenarios, Henning Hermjakob

Research output: Contribution to journalArticlepeer-review


The International Molecular Exchange (IMEx) consortium is an international collaboration between major public interaction data providers to share literature-curation efforts and make a nonredundant set of protein interactions available in a single search interface on a common website (http://www. Common curation rules have been developed, and a central registry is used to manage the selection of articles to enter into the dataset. We discuss the advantages of such a service to the user, our quality-control measures and our data-distribution practices.

Original languageEnglish
Pages (from-to)345-350
Number of pages6
JournalNature Methods
Issue number4
Publication statusPublished - Apr 2012

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Biology
  • Biochemistry
  • Cell Biology


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