Protein misfolding, amyotrophic lateral sclerosis and guanabenz: Protocol for a phase II RCT with futility design (ProMISe trial)

E.D. Bella, I. Tramacere, G. Antonini, G. Borghero, M. Capasso, C. Caponnetto, A. Chiò, M. Corbo, R. Eleopra, M. Filosto, F. Giannini, E. Granieri, V.L. Bella, C. Lunetta, J. Mandrioli, L. Mazzini, S. Messina, M.R. Monsurrò, G. Mora, N. RivaR. Rizzi, G. Siciliano, V. Silani, I. Simone, G. Sorarù, P. Volanti, G. Lauria

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Bella, E. D., Tramacere, I., Antonini, G., Borghero, G., Capasso, M., Caponnetto, C., Chiò, A., Corbo, M., Eleopra, R., Filosto, M., Giannini, F., Granieri, E., Bella, V. L., Lunetta, C., Mandrioli, J., Mazzini, L., Messina, S., Monsurrò, M. R., Mora, G., ... Lauria, G. (2017). Protein misfolding, amyotrophic lateral sclerosis and guanabenz: Protocol for a phase II RCT with futility design (ProMISe trial). BMJ Open, 7(8). https://doi.org/10.1136/bmjopen-2016-015434