Protein S and protein C anticoagulant activity in acute and chronic cardiac ischemic syndromes. Relationship to inflammation, complement activation and in vivo thrombin activity

Armando D'Angelo; Stefano Gerosa; Silvana Vigano' D'Angelo; Alessandra Mailhac; Alessandro Colombo; Alberto Agazzi; Giuseppina Mazzola; Sergio Chierchia

doi:10.1016/0049-3848(94)90062-0

Protein S and protein C anticoagulant activity in acute and chronic cardiac ischemic syndromes. Relationship to inflammation, complement activation and in vivo thrombin activity

Armando D'Angelo, Stefano Gerosa, Silvana Vigano' D'Angelo, Alessandra Mailhac, Alessandro Colombo, Alberto Agazzi, Giuseppina Mazzola, Sergio Chierchia

Research output: Contribution to journal › Article

Abstract

Protein S (PS) and protein C (PC) anticoagulant activities and thrombin-antithrombin complex (TAT) were measured in 20 patients with AIS, 25 patients with chronic stable angina (CSA) and a control group (C). Although plasma levels of TAT were significantly elevated in patients with CSA (p p>0.005 vs C). In addition, the ratios of anticoagulant PC and PS to factor IX were lower in patients with AIS than in those with CSA (p

Original language	English
Pages (from-to)	133-142
Number of pages	10
Journal	Thrombosis Research
Volume	75
Issue number	2
DOIs	https://doi.org/10.1016/0049-3848(94)90062-0
Publication status	Published - Jul 15 1994

Keywords

complement
hypercoagulability
ischemic heart disease
protein S
thrombin-antithrombin complex
vitamin K-dependent factors
von Willebrand factor

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Hematology

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10.1016/0049-3848(94)90062-0

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D'Angelo, A., Gerosa, S., Vigano' D'Angelo, S., Mailhac, A., Colombo, A., Agazzi, A., Mazzola, G., & Chierchia, S. (1994). Protein S and protein C anticoagulant activity in acute and chronic cardiac ischemic syndromes. Relationship to inflammation, complement activation and in vivo thrombin activity. Thrombosis Research, 75(2), 133-142. https://doi.org/10.1016/0049-3848(94)90062-0

Protein S and protein C anticoagulant activity in acute and chronic cardiac ischemic syndromes. Relationship to inflammation, complement activation and in vivo thrombin activity. / D'Angelo, Armando; Gerosa, Stefano; Vigano' D'Angelo, Silvana; Mailhac, Alessandra; Colombo, Alessandro; Agazzi, Alberto; Mazzola, Giuseppina; Chierchia, Sergio.

In: Thrombosis Research, Vol. 75, No. 2, 15.07.1994, p. 133-142.

Research output: Contribution to journal › Article

D'Angelo, A, Gerosa, S, Vigano' D'Angelo, S, Mailhac, A, Colombo, A, Agazzi, A, Mazzola, G & Chierchia, S 1994, 'Protein S and protein C anticoagulant activity in acute and chronic cardiac ischemic syndromes. Relationship to inflammation, complement activation and in vivo thrombin activity', Thrombosis Research, vol. 75, no. 2, pp. 133-142. https://doi.org/10.1016/0049-3848(94)90062-0

D'Angelo, Armando ; Gerosa, Stefano ; Vigano' D'Angelo, Silvana ; Mailhac, Alessandra ; Colombo, Alessandro ; Agazzi, Alberto ; Mazzola, Giuseppina ; Chierchia, Sergio. / Protein S and protein C anticoagulant activity in acute and chronic cardiac ischemic syndromes. Relationship to inflammation, complement activation and in vivo thrombin activity. In: Thrombosis Research. 1994 ; Vol. 75, No. 2. pp. 133-142.

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