Proteinuria in diabetic nephropathy: Treatment and evolution

Ruth C. Campbell, Piero Ruggenenti, Giuseppe Remuzzi

Research output: Contribution to journalArticlepeer-review

Abstract

Diabetic nephropathy is characterized by increased urinary albumin excretion and loss of renal function. Increased urinary albumin (proteinuria) is a key component of this disease. Previously, its development led to end-stage renal disease with increased mortality and morbidity for diabetic patients versus nondiabetic patients. Several treatment strategies currently exist that can prevent, slow, and even reverse diabetic nephropathy. New trials suggest that a multidisciplinary approach focused on optimizing metabolic and hypertensive control, in addition to the use of angiotensin-converting enzyme inhibitors or angiotensin 2 receptor antagonists, is effective in halting the progression of disease. Screening and implementation of these strategies is needed to reverse the epidemic of diabetic renal disease.

Original languageEnglish
Pages (from-to)497-504
Number of pages8
JournalCurrent Diabetes Reports
Volume3
Issue number6
Publication statusPublished - Dec 2003

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

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