TY - JOUR
T1 - Proteomic applications in food allergy
T2 - Food allergenomics
AU - Di Girolamo, Francesco
AU - Muraca, Maurizio
AU - Mazzina, Oscar
AU - Lante, Isabella
AU - Dahdah, Lamia
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Purpose of review To familiarize the reader with the recent developments in the identification of food protein allergens by proteomics mass spectrometry-based methods, named allergenomics. Recent findings The proteomic analysis of food protein allergens has became a hot topic in the food safety field in recent years. Indeed, food allergies represent a current and relevant problem in clinical medicine. Several food allergenomics studies have recently been performed, aiming at better understanding the cause of sensitization to cow's milk in breastfed infants and at assessing both the safety of food (e.g. transgenic) and in particular the allergenic properties of processed fish and seafood. Summary Food protein allergen characterization and quantification, together with the immunoglobulin E epitope mapping, will contribute to the diagnosis/prognosis of food allergy and will lead to a better safety assessment of foods (e.g. novel transgenic foods).
AB - Purpose of review To familiarize the reader with the recent developments in the identification of food protein allergens by proteomics mass spectrometry-based methods, named allergenomics. Recent findings The proteomic analysis of food protein allergens has became a hot topic in the food safety field in recent years. Indeed, food allergies represent a current and relevant problem in clinical medicine. Several food allergenomics studies have recently been performed, aiming at better understanding the cause of sensitization to cow's milk in breastfed infants and at assessing both the safety of food (e.g. transgenic) and in particular the allergenic properties of processed fish and seafood. Summary Food protein allergen characterization and quantification, together with the immunoglobulin E epitope mapping, will contribute to the diagnosis/prognosis of food allergy and will lead to a better safety assessment of foods (e.g. novel transgenic foods).
KW - allergenomics
KW - food allergens
KW - mass spectrometry
KW - proteomics
UR - http://www.scopus.com/inward/record.url?scp=84959567129&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959567129&partnerID=8YFLogxK
U2 - 10.1097/ACI.0000000000000160
DO - 10.1097/ACI.0000000000000160
M3 - Article
C2 - 25899690
AN - SCOPUS:84959567129
VL - 15
SP - 259
EP - 266
JO - Current Opinion in Allergy and Clinical Immunology
JF - Current Opinion in Allergy and Clinical Immunology
SN - 1528-4050
IS - 3
ER -