A study is presented of 401 subjects with liver disorders of different type; the prothrombin activity in each was compared to the results of several liver function tests performed simultaneously e.g. Takata McLagan test, plasma gamma globulin percentage and BSP. The results demonstrated that the extent of deviation of each single test corresponded to the degree of decreased prothrombin activity. Another observation was the different relationship in the various liver diseases between the reduced prothrombin activity and the abnormal function tests. Therefore, it does not seem possible to establish a direct or valid relationship between the values of liver function tests and the levels of the prothrombin activity. These observations possess remarkable clinical interest, i.e. not so much with regard to the diagnostic effects as to the effects of a physiopathological interpretation with different prognostic and therapeutic implications in the various types of liver disease.
|Translated title of the contribution||Prothrombin activity in the context of the functional impairment in various hepatopathies|
|Number of pages||15|
|Publication status||Published - 1973|
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