Protocol to verify the comparability of quantitative laboratory results obtained with different measurement procedures

Matteo Vidali, Andrea Padoan, Ruggero Dittadi, Duilio Brugnoni, Anna Carobene, Sonia Mattioli, Laura Sciacovelli, Ferruccio Ceriotti

Research output: Contribution to journal › Review article

1 Citation (Scopus)

Abstract

© 2019 Biomedia. All rights reserved. With the growth and merging of clinical laboratories, very frequently analytical tests are performed on multiple instruments within one or multiple locations. In these situations, there is the need of verifying the comparability of patient results obtained with different analysers and/or different measurement procedures. The importance of this verification is further emphasised when considering that it is included into the ISO 15189 specifications. This protocol provides step-by-step guidance on how to assess results comparability in different scenarios. Up to four experimental designs are presented to meet laboratories' needs, with details and examples on frequency of testing, definition of acceptability criteria, samples selection, sample size calculation, statistical analysis and reporting.
Original languageEnglish
Pages (from-to)228-243
Number of pages16
JournalBiochimica Clinica
Volume43
Issue number2
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Clinical laboratories
Merging
Design of experiments
Statistical methods
Specifications
Network protocols
Testing
Sample Size
Patient Selection
Research Design
Growth

Cite this

Protocol to verify the comparability of quantitative laboratory results obtained with different measurement procedures. / Vidali, Matteo; Padoan, Andrea; Dittadi, Ruggero; Brugnoni, Duilio; Carobene, Anna; Mattioli, Sonia; Sciacovelli, Laura; Ceriotti, Ferruccio.

In: Biochimica Clinica, Vol. 43, No. 2, 01.01.2019, p. 228-243.

Research output: Contribution to journal › Review article

Vidali, M, Padoan, A, Dittadi, R, Brugnoni, D, Carobene, A, Mattioli, S, Sciacovelli, L & Ceriotti, F 2019, 'Protocol to verify the comparability of quantitative laboratory results obtained with different measurement procedures', Biochimica Clinica, vol. 43, no. 2, pp. 228-243. https://doi.org/10.19186/BC_2019.047
Vidali M, Padoan A, Dittadi R, Brugnoni D, Carobene A, Mattioli S et al. Protocol to verify the comparability of quantitative laboratory results obtained with different measurement procedures. Biochimica Clinica. 2019 Jan 1;43(2):228-243. https://doi.org/10.19186/BC_2019.047
Vidali, Matteo ; Padoan, Andrea ; Dittadi, Ruggero ; Brugnoni, Duilio ; Carobene, Anna ; Mattioli, Sonia ; Sciacovelli, Laura ; Ceriotti, Ferruccio. / Protocol to verify the comparability of quantitative laboratory results obtained with different measurement procedures. In: Biochimica Clinica. 2019 ; Vol. 43, No. 2. pp. 228-243.
@article{0d99d0221cb54c4bac8b3eda130d89d0,
title = "Protocol to verify the comparability of quantitative laboratory results obtained with different measurement procedures",
abstract = "{\circledC} 2019 Biomedia. All rights reserved. With the growth and merging of clinical laboratories, very frequently analytical tests are performed on multiple instruments within one or multiple locations. In these situations, there is the need of verifying the comparability of patient results obtained with different analysers and/or different measurement procedures. The importance of this verification is further emphasised when considering that it is included into the ISO 15189 specifications. This protocol provides step-by-step guidance on how to assess results comparability in different scenarios. Up to four experimental designs are presented to meet laboratories' needs, with details and examples on frequency of testing, definition of acceptability criteria, samples selection, sample size calculation, statistical analysis and reporting.",
author = "Matteo Vidali and Andrea Padoan and Ruggero Dittadi and Duilio Brugnoni and Anna Carobene and Sonia Mattioli and Laura Sciacovelli and Ferruccio Ceriotti",
year = "2019",
month = "1",
day = "1",
doi = "10.19186/BC_2019.047",
language = "English",
volume = "43",
pages = "228--243",
journal = "Biochimica Clinica",
issn = "0393-0564",
publisher = "CLAS International",
number = "2",

}

TY - JOUR

T1 - Protocol to verify the comparability of quantitative laboratory results obtained with different measurement procedures

AU - Vidali, Matteo

AU - Padoan, Andrea

AU - Dittadi, Ruggero

AU - Brugnoni, Duilio

AU - Carobene, Anna

AU - Mattioli, Sonia

AU - Sciacovelli, Laura

AU - Ceriotti, Ferruccio

PY - 2019/1/1

Y1 - 2019/1/1

N2 - © 2019 Biomedia. All rights reserved. With the growth and merging of clinical laboratories, very frequently analytical tests are performed on multiple instruments within one or multiple locations. In these situations, there is the need of verifying the comparability of patient results obtained with different analysers and/or different measurement procedures. The importance of this verification is further emphasised when considering that it is included into the ISO 15189 specifications. This protocol provides step-by-step guidance on how to assess results comparability in different scenarios. Up to four experimental designs are presented to meet laboratories' needs, with details and examples on frequency of testing, definition of acceptability criteria, samples selection, sample size calculation, statistical analysis and reporting.

AB - © 2019 Biomedia. All rights reserved. With the growth and merging of clinical laboratories, very frequently analytical tests are performed on multiple instruments within one or multiple locations. In these situations, there is the need of verifying the comparability of patient results obtained with different analysers and/or different measurement procedures. The importance of this verification is further emphasised when considering that it is included into the ISO 15189 specifications. This protocol provides step-by-step guidance on how to assess results comparability in different scenarios. Up to four experimental designs are presented to meet laboratories' needs, with details and examples on frequency of testing, definition of acceptability criteria, samples selection, sample size calculation, statistical analysis and reporting.

UR - http://www.scopus.com/inward/record.url?scp=85070689422&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85070689422&partnerID=8YFLogxK

U2 - 10.19186/BC_2019.047

DO - 10.19186/BC_2019.047

M3 - Review article

AN - SCOPUS:85070689422

VL - 43

SP - 228

EP - 243

JO - Biochimica Clinica

JF - Biochimica Clinica

SN - 0393-0564

IS - 2

ER -

Access to Document