Proviral DNA of Moloney leukemia virus: purification and visualization

A. M. Gianni, J. R. Hutton, D. Smotkin, R. A. Weinberg

Research output: Contribution to journalArticlepeer-review


Closed circular proviral DNA of Moloney leukemia virus has been purified from a 107 excess of cellular and mitochondrial DNA. The DNA can be visualized in the electron microscope and has the contour length of a molecule with a molecular weight of about 5.5 x 106. Electron microscopic observation of a hybrid between viral RNA and this circular DNA confirms the viral origin of this molecule.

Original languageEnglish
Pages (from-to)569-571
Number of pages3
Issue number4227
Publication statusPublished - 1976

ASJC Scopus subject areas

  • General


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