Abstract
Although the relationship between psyche and cancer dates back many centuries ago and several studies have been conducted on this topic during the last decades, the role of psychological factors in the cancer development is still controversial. Although a lot of factors have been considered, attention has been focused mainly on stress, which has been evaluated also in experimental models. Generally, the results of case-control studies have been contradictory, and at times more stressfull events have been recorded in patients with benign tumors than in those witii cancer. On the contrary, a higher incidence of stress-related cancers has not been documented in cohort studies. Since cancer is a genetic disease, it is difficult to hypothesize that psychological factors may permanently alter nucleotide sequence giving rise to multiple mutations needed for cancer development. At present, there is no sufficient evidence to affirm that psychological factors may contribute without doubt to cancer development.
| Original language | Italian |
|---|---|
| Pages (from-to) | 69-75 |
| Number of pages | 7 |
| Journal | Clinica Terapeutica |
| Volume | 161 |
| Issue number | 1 |
| Publication status | Published - Jan 2010 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Psiche e cancro. / Lopez, Massimo; Cauchi, C.; Sergi, D.; Amodio, A.; Paoletti, G.; Vici, P.; Di Lauro, L.
In: Clinica Terapeutica, Vol. 161, No. 1, 01.2010, p. 69-75.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Psiche e cancro
AU - Lopez, Massimo
AU - Cauchi, C.
AU - Sergi, D.
AU - Amodio, A.
AU - Paoletti, G.
AU - Vici, P.
AU - Di Lauro, L.
PY - 2010/1
Y1 - 2010/1
N2 - Although the relationship between psyche and cancer dates back many centuries ago and several studies have been conducted on this topic during the last decades, the role of psychological factors in the cancer development is still controversial. Although a lot of factors have been considered, attention has been focused mainly on stress, which has been evaluated also in experimental models. Generally, the results of case-control studies have been contradictory, and at times more stressfull events have been recorded in patients with benign tumors than in those witii cancer. On the contrary, a higher incidence of stress-related cancers has not been documented in cohort studies. Since cancer is a genetic disease, it is difficult to hypothesize that psychological factors may permanently alter nucleotide sequence giving rise to multiple mutations needed for cancer development. At present, there is no sufficient evidence to affirm that psychological factors may contribute without doubt to cancer development.
AB - Although the relationship between psyche and cancer dates back many centuries ago and several studies have been conducted on this topic during the last decades, the role of psychological factors in the cancer development is still controversial. Although a lot of factors have been considered, attention has been focused mainly on stress, which has been evaluated also in experimental models. Generally, the results of case-control studies have been contradictory, and at times more stressfull events have been recorded in patients with benign tumors than in those witii cancer. On the contrary, a higher incidence of stress-related cancers has not been documented in cohort studies. Since cancer is a genetic disease, it is difficult to hypothesize that psychological factors may permanently alter nucleotide sequence giving rise to multiple mutations needed for cancer development. At present, there is no sufficient evidence to affirm that psychological factors may contribute without doubt to cancer development.
KW - Cancer
KW - Depression
KW - Psyche
KW - Psychological factors
KW - Stress
UR - http://www.scopus.com/inward/record.url?scp=77950221256&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950221256&partnerID=8YFLogxK
M3 - Articolo
VL - 161
SP - 69
EP - 75
JO - Clinica Terapeutica
JF - Clinica Terapeutica
SN - 0009-9074
IS - 1
ER -