Abstract
At Alzheimer' disease (AD) onset, psychiatric symptoms like anxiety, insomnia, depression, motor retardation, delusions, hallucinations, agitation can be of great importance. Psychopathological symptoms are described in 1/3 of patients. 13 patients affected by AD at its onset, of both sexes, age ranging from 45 to 80 years (mean 65.46 years ± 12.31 SD) were included in the study. Our study showed that psychopathological symptoms, particularly depression, agitation and eating disorders, negatively influenced patients' ability to carry out the most common daily tasks. No relation was found between cognitive deterioration and worsening of behavioural aspects. From a neuromorphological point of view, lobe atrophy (frontal and parietal) was negatively correlated to depressive symptomatology. Despite the small number of the patients studied, it seems that at AD onset, when cortical atrophy and correlated cognitive impairment are of less degree, the change in mood, becomes prominent.
| Original language | English |
|---|---|
| Pages (from-to) | 93-98 |
| Number of pages | 6 |
| Journal | New Trends in Experimental and Clinical Psychiatry |
| Volume | 14 |
| Issue number | 2 |
| Publication status | Published - 1998 |
Fingerprint
Keywords
- Alzheimer's disease
- Cognitive symptoms
- Depression
- Neuromorphology
ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
Psychiatric, cognitive and neuromorphological aspects in the earlier phases of Alzheimer's disease. / Mauri, M. C.; Steinhilber, C. P C; Laini, V.; Longhini, U.
In: New Trends in Experimental and Clinical Psychiatry, Vol. 14, No. 2, 1998, p. 93-98.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Psychiatric, cognitive and neuromorphological aspects in the earlier phases of Alzheimer's disease
AU - Mauri, M. C.
AU - Steinhilber, C. P C
AU - Laini, V.
AU - Longhini, U.
PY - 1998
Y1 - 1998
N2 - At Alzheimer' disease (AD) onset, psychiatric symptoms like anxiety, insomnia, depression, motor retardation, delusions, hallucinations, agitation can be of great importance. Psychopathological symptoms are described in 1/3 of patients. 13 patients affected by AD at its onset, of both sexes, age ranging from 45 to 80 years (mean 65.46 years ± 12.31 SD) were included in the study. Our study showed that psychopathological symptoms, particularly depression, agitation and eating disorders, negatively influenced patients' ability to carry out the most common daily tasks. No relation was found between cognitive deterioration and worsening of behavioural aspects. From a neuromorphological point of view, lobe atrophy (frontal and parietal) was negatively correlated to depressive symptomatology. Despite the small number of the patients studied, it seems that at AD onset, when cortical atrophy and correlated cognitive impairment are of less degree, the change in mood, becomes prominent.
AB - At Alzheimer' disease (AD) onset, psychiatric symptoms like anxiety, insomnia, depression, motor retardation, delusions, hallucinations, agitation can be of great importance. Psychopathological symptoms are described in 1/3 of patients. 13 patients affected by AD at its onset, of both sexes, age ranging from 45 to 80 years (mean 65.46 years ± 12.31 SD) were included in the study. Our study showed that psychopathological symptoms, particularly depression, agitation and eating disorders, negatively influenced patients' ability to carry out the most common daily tasks. No relation was found between cognitive deterioration and worsening of behavioural aspects. From a neuromorphological point of view, lobe atrophy (frontal and parietal) was negatively correlated to depressive symptomatology. Despite the small number of the patients studied, it seems that at AD onset, when cortical atrophy and correlated cognitive impairment are of less degree, the change in mood, becomes prominent.
KW - Alzheimer's disease
KW - Cognitive symptoms
KW - Depression
KW - Neuromorphology
UR - http://www.scopus.com/inward/record.url?scp=0031663144&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031663144&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0031663144
VL - 14
SP - 93
EP - 98
JO - New Trends in Experimental and Clinical Psychiatry
JF - New Trends in Experimental and Clinical Psychiatry
SN - 0393-5310
IS - 2
ER -