Autosomal Dominant Cortical Tremor, Myoclonus and Epilepsy (ADCME) is an inherited condition characterized by familial occurrence of cortical tremor, myoclonus and epileptic seizures. We assessed psychiatric comorbidity in a subgroup of fourteen ADCME/BAFME patients by using reliable and valid psychodiagnostic scales, such BDI (Beck Depression Inventory), STAI-Y (State-Trait Anxiety Inventory Y), MMPI-2 (Minnesota Multiphasic Personality Inventory-2) and QoLIE-31 (Quality-of-Life in Epilepsy Inventory). This pilot study first confirms a high prevalence of mood disorders, particularly depression and anxiety, in ADCME patients, often associated to pathological traits of personality. A statistically significant correlation is present between anxiety and myoclonus severity. Moreover these patients show a worse quality of life compared to other patients presenting only with seizures.
|Translated title of the contribution||Psychiatric features in families with autosomal dominant cortical tremor, myoclonus and epilepsy|
|Number of pages||4|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - Apr 2013|
ASJC Scopus subject areas
- Clinical Neurology